vehicle containing propylene glycol, and the area treated became excoriated. After recovery to baseline renal function, cidofovir 1% gel once daily was started with excellent response and no side-effects. 10 No studies have been performed to investigate the bioavailability of topical or intralesional cidofovir in humans. 8 Rabbit studies suggest that propylene glycol, abrasion and occlusion increase skin absorption. 11 We did not monitor renal function in our patients, as blood tests are considered more invasive in the paediatric population and we were applying 1% concentration with ointment vehicle only (no propylene glycol). Application was under occlusion but patients were closely monitored for excoriation, inflammation or erosions.Cost is a limiting factor for the use of cidofovir. Cidofovir is however a relatively noninvasive therapy and a balance between cost efficacy and treatment morbidity should be considered. At this stage, treatment with cidofovir should probably be reserved for patients with severe persistent, resistant and symptomatic viral warts who have been compliant with previous treatments.In this retrospective study, four of the seven children with recalcitrant viral warts achieved long-lasting clearance in response to topical 1% cidofovir. There were no significant safety issues. This series supports the need for further studies to investigate therapeutic efficacy, safety and, importantly, cost effectiveness of cidofovir 1% ointment. Reference1 McKenna DJ, McGlennon S, McCallum M, Dolan OM. Evaluation of a novel 'needlecatcher' surgical instrument designed to reduce the incidence of needle stick injuries from suture needles during skin suturing. Br J Dematol 2008; 158:649-51.

Recurrent discharging sinus of the port site after laparoscopic Cholecystectomy is an uncommon complication of spilled, missed gall stones. The chronically discharging sinus may mimic atypical mycobacterial infection of the port site or neoplasm. High index of suspicion must be maintained to diagnose this rare complication of port sites due to missed stones while retrieving the gall bladder specimen through the port openings. Port site complications not only add to the stress and morbidity to the patient, but also undermine the benefits of minimal invasive surgery. Awareness of this entity is important in order to develop preventive protocol, in future.