The article of the current state of small and medium-sized businesses in the Russian Federation is discussed. The problems that unlike the countries of Western Europe, hamper the harmonious development of small and medium-sized businesses are noted. Most attention is paid to the problems of small and medium-sized businesses in rural areas. A large imbalance has been established between the number of small and medium-sized enterprises in rural areas and the city. The results of studies in the form of diagrams are presented. The reasons for the large difference in the number of small and medium-sized enterprises between the countryside and the city are determined. It is noted that the emergence of a large number of urban-type villages in rural areas near large cities does not change the situation. Areas of activity in which small and medium-sized businesses will more conveniently develop in rural areas are identified. Conditions have been established that will contribute to the development of small and medium-sized enterprises in rural areas. The proposals for improving the efficiency of small and medium-sized businesses in rural areas in the Russian Federation are presented. Particular attention in the proposals is given to the problem of reducing the young population in rural areas. Therefore, the submitted proposals take into account the strategic and socio-economic aspects of the development of small and medium-sized enterprises in the Russian Federation. It is noted that this approach to solving problems is used in Western Europe.

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Hierarchical population structure can result from range-wide geographic subdivision under conditions of environmental heterogeneity and weak gene flow. While a lower level of structure can be formed by local populations within eco-geographic regions, an upper level can be characterized by variation between populations from different regions, and thus, be represented by evolutionarily significant units (ESUs) defined by environmental, ecological and genetic variation. Selection of ESUs may depend on the sequence of using these three sources of variation. We propose to determine ESUs by first using non-genetic, ecological and geographical gradients for defining preliminary population groups (eco-geographic units, EGUs) and then testing whether the boundaries of these units are genetically coherent and thus represent ESUs or warrant their further modification. We evaluate this approach using Sakhalin taimen, an East Asian endangered endemic fish. Forty-one samples (473 fish) were drawn from thirty populations across the species range and genotyped at microsatellite DNA markers. We assign the populations into ESUs based on geographic and life history criteria and subsequent application of genetic diversity analyses. The ESUs appeared to be greatly diverged genetically. Within ESUs, local populations are genetically differentiated, have low effective sizes, show signatures of demographic decline and extremely restricted gene flow. Conservation plans aimed to restore or maintain a specific threatened population should take into account such hierarchical structure, and in particular be based on the genetic resources drawn from each population or using ecologically and genetically similar populations from the same ESU as donors for restoration of the population.

The necessity of developing a mathematical model for converting the recorded NMR signal using a modulation technique into the spectrum for conducting the composition of the medium under study is substantiated. A mathematical model has been developed to represent the NMR signal in the form of a spectrum, taking into account the features of its registration from condensed matter. Spectra of calculated and experimental NMR signals are presented. Them comparison are completed.

The results of the research presented in the article relate to modernization of wastewater treatment and environmental safety technology of remediation nature water after pollution. Have been showed his main criteria and condition of the using of plants in wastewater treatment for protecting ingress of substances into natural reservoirs and causing negative effects such as eutrophication and secondary pollution. The type of plants was selected with taking into account the environmental potential of water treatment on the basis of analysis of the data obtained. Continued for the use technology with plants help to preserve natural reservoirs for drinking for the future.