Titanium dioxide TiO2 has witnessed great interest in international research laboratories due to its excellent properties. To study the changes in its physical properties, the structural properties of pure and lead-doped titanium dioxide powder samples were examined with different ratios (x = 0.2 - 0.5 - 0.7 - 0.9 g). The results of X-ray diffraction showed the participation of samples of anatase and rutile of the tetragonal crystal system and brookite of the orthorhombic crystal system based in the titanium dioxide compound with the peaks corresponding to the crystalline levels (110), (012), (040), (111), (211), (123), (112)The preferred orientation is (110) in all pure and doped samples. The relative intensities, distance between crystalline planes (d), crystal size (D), lattice parameters (a), (b) and (c), Initial cell size (V), dislocation density (δ), and theoretical density of the X-ray diffraction spectrum for the powders (ρX-ray) were determined, and the number of atoms of a substance per unit volume (n) and the average distance between atoms (L).