We simulate the space-time dynamics of high-energy collisions based on a microscopic kinetic description, in order to determine the range of applicability of an effective description in relativistic viscous hydrodynamics. We find that hydrodynamics provides a quantitatively accurate description of collective flow when the average inverse Reynolds number Re −1 is sufficiently small and the early pre-equilibrium stage is properly accounted for. By determining the breakdown of hydrodynamics as a function of system size and energy, we find that it is quantitatively accurate in central lead-lead collisions at LHC energies, but should not be used in typical proton-lead or protonproton collisions, where the development of collective flow can not accurately be described within hydrodynamics.

We employ an effective kinetic description to study the space-time dynamics and development of transverse flow of small and large collision systems. By combining analytical insights in the few interactions limit with numerical simulations at higher opacity, we are able to describe the development of transverse flow from very small to very large opacities, realised in small and large collision systems. Surpisingly, we find that deviations between kinetic theory and hydrodynamics persist even in the limit of very large interaction rates, which can be attributed to the presence of the early pre-equilibrium phase.