Malignant fibrous histiocytoma (MFH) is widely regarded as the commonest soft tissue sarcoma of adulthood which tends to occur in the deep soft tissues of the extremities and the retroperitoneum. Uncertain histogenesis and numerous subtypes make MFH a rather controversial entity. These tumours are relatively rare in the head and neck region accounting for only 1-3% of all cases of MFH. MFH exhibits a heterogenous histology of spindle cells in a characteristic storiform pattern with pleomorphic tumour cells and giant cells. A case is reported of an MFH of the gingiva in a 60-year-old woman who presented with a painful swelling originating from the left maxillary gingiva. The clinical, histopathological and immunohistochemical findings are discussed.

There was a 19% increase in year 2021 when compared to 2020 in TB patients’ notification in India, even though TB notifications noted around the period corresponding to India’s two major COVID-19 waves showed a brief decline, the National Tuberculosis Elimination Programme (NTEP) managed to reclaim the lost numbers. Cystic changes of the soft tissue and chest wall associated with pulmonary tuberculosis is rarely diagnosed and reported, and only few patients were diagnosed based only on the radiological and histopathological findings. Herewith, we report the microbiological, histopathological, computed tomographic, ultrasound and clinical findings of cystic change in pulmonary tuberculosis in an immunocompetent 18-year-old male who presented with pain in the Chest and swelling in the left infra mammary region for a short duration of one month. The lesion regressed and patient showed clinical improvement following Anti-tuberculous therapy treatment initiation after linking the patient with NIKSHAY system and is currently under ATT.

Background Although some age-related changes in lymph node histoarchitecture have been described, they are seldom taken into account in traditional depictions of lymph nodes. Recently introduced clinical procedures, such as intranodal vaccinations have demonstrated the need for an accurate knowledge of the degenerative processes of lymph nodes. It is thus deemed necessary to obtain a detailed insight into anatomical changes within the lymph node throughout life as age-related degeneration can have a strong impact on the outcome of these new therapeutic strategies. Aim To study the size and shape of the lymph nodes and to establish the age-dependent histoarchitectural changes in the lymph nodes in different age groups. Materials and Methods A cross-sectional study was conducted in a total of 35 axillary lymph nodes. The adult axillary group of lymph nodes were from subjects aged between 18 and 70 years. The fetal lymph nodes were collected from 8 stillborn fetuses between 37 and 42 weeks. Thickness of the cortex and diameter of the germinal centers were measured using ocular and stage micrometer. Results None of the fetal lymphocytic follicles showed evidence of a prominent germinal center. The germinal centers of young adults were not only more numerous but also larger in size when compared with the old. An age-related involution of the paracortical region was witnessed in the axillary lymph nodes. No evidence of lipomatous atrophy was encountered in any of the fetal lymph nodes. Interesting evidence of it was encountered in younger age groups. However, this was the most prominent feature in the older groups.