Background: Testis is the site for a large number of neoplastic and non-neoplastic lesions of varied etiology which can occur in any age group. Testicular tumours are rare, affecting adolescents and young adults. Only limited literature is available on the epidemiology of testicular and paratesticular lesions from South India. Aim: A detailed 4 year histopathological analysis of testicular and paratesticular lesions including testicular tumours were undertaken. Materials and Methods: A total of 160 orchidectomy cases studied with retrieved blocks and slides from the department. A detailed clinicopathological correlation done. Serological markers and Immunohistochemistry done in required cases. Results: Our analysis showed 87.5% non neoplastic lesions with torsion testis being the most common followed by atrophic testis and tuberculous epididymo-orchitis. Of the neoplastic lesions (12.5%) malignant tumours were common compared to benign tumours and germ cell tumour constituted the predominant malignant lesion. Conclusion:The distribution of testicular lesions in patients attending our institution were comparable with available worldwide data.

BACKGROUND Pancytopenia is an important clinico-haematological entity encountered in our daily clinical practice. There are varying clinical patterns, treatment modalities and outcomes for pancytopenia. The severity of pancytopenia and the underlying pathology determine the management and prognosis of the patient. Hence, the evaluation of the various causes of pancytopenia could aid in planning the diagnostic and therapeutic approach in patients with pancytopenia. Megaloblastic anaemia is one of the major causes of pancytopenia in India. The objectives are to identify the various causes of pancytopenia, to describe the clinical and haematological parameters in pancytopenia. MATERIALS AND METHODS A descriptive study on 80 cases was conducted to describe the various causes of pancytopenia in the peripheral blood, bone marrow aspirate and trephine biopsy samples of pancytopenia patients received in the Department of Pathology, Government Medical College, Kottayam during a period of 12 months (June 2016-May 2017). RESULTS Among the 80 cases of pancytopenia studied, common causes were megaloblastic anaemia (18 cases, 23%) and acute lymphoblastic leukaemia (9 cases, 11%). Majority of the patients had a hypercellular bone marrow (70%). CONCLUSION Most common cause of pancytopenia was megaloblastic anaemia followed by acute leukaemia.

No abstract

No abstract