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ABSRACT:A 50-year-old man presented to hospital with non-specific symptoms such as anorexia, nausea, dehydration, weight loss, fatigue, generalized weakness, and lethargy. His Serum level of calcium was markedly increased 16.2 mg/dL (8.6-10.2 mg/dL) and parathyroid hormone (PTH) was 9.4 IU (2-11 IU), CT Abdomen was S/O leiomyosarcoma of stomach, upper GI scopy revealed growth in mid esophagus, biopsy was done and histology showed squamous cell carcinoma. Hypercalcemia was corrected and patient improved.

Periodontal disease is one of the earliest human diseases recognized to be associated with mixed-species biofilms. One of the microorganism involved in this biofilm include Candida species which have been invariably found in large quantities in subgingival area of patients having periodontal disease. This paper reviews the prevalence of Candida species in periodontal disease as well as their virulence factors and identification methods.

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