The application of agro-waste in the form of compost is an ecofriendly approach to minimize the use of chemicals for crop improvement. Hence, compost was prepared by the Indore method from banana spathe obtained from five popular varieties of banana cultivated in Tamil Nadu, India, and its growth promoting ability was tested on the rice cultivar CO-51. The banana spathe was applied as both an aqueous extract and compost to evaluate the growth parameters in bioassays and pot culture experiments. The compost improved the growth in terms of root length, shoot length, biomass, tillers, length, and width of flag leaf and yield in CO-51 rice cultivar significantly (p < 0.001%) when compared to the untreated control and fertilizer-treated plants. The maximum yield was observed in the treatment with Rasthali spathe. Biochemical analysis of the compost-treated rice plants showed an increase in chlorophyll, carotenoid, carbohydrate, protein, and amino acid content when compared to the untreated control plants. The results from the study suggest that the banana spathe compost could be used as an effective organic fertilizer for the growth of rice plants thus providing a strategy to reduce landfills, as well as the use of fertilizers, thereby further helping to protect the agroecosystem.

Medicinal plants possess pharmacological effect due to the presence of bioactive compounds. The target of this presence study is find out the bioactive chemical constituents and to evaluate anti proliferative effect and also analyze the larvicidal effect of methanolic and aqueous extract of dried leaves of canavalia virosa. The preliminary study shows this plant contains the presence of secondary metabolites like alkaloids, flavonoids, saponins, phytosteroids, steroids, tannins, terpenoids and coumarins. This research reports methanolic extract of canavalia virosa shows antiproliferative activity effect against Sk- Mel 2 cells. The larvicidal activity of canavalia virosa was performed against the 4th instar larvae of anopheles mosquitoes. The larvicidal mortality was observed after 48hours of plant extract exposure. This is an ecofriendly approach for mosquitoes control measure. The results of this present study shows the plant has potential effect against mosquitoes and has antiproliferative effect.

ARTICLE INFO ABSTRACTThe main aim of this study was to evaluate the incidence of ADRs, the patients who are receiving or taking antihypertensive medications. ADR monitoring is an important part of post marketing surveillance which helps in generating data safety of medications. Main aim to ADRs monitoring is to the promoting rational use of drugs, safe use of medicines improving patient care, improving public health. This was a prospective, observational, voluntary reporting study. Study was conducted in and around Coimbatore. Samples are collected in all age group. We are taken support of 'Suspected Adverse Drug Reaction Reporting form from IPC to collect samples. A total of 34 adverse drug reactions were observed in hypertensive patients during the 3 months study. A high percentage of adverse drug reaction occurred in middle age and female patients. Combination therapy was high occurrence of adverse drug reaction as compared to immunotherapy. Cardiovascular adverse drug reactions constituted a major component, followed by gastrointestinal and respiratory complaints. Beta-blockers were the drug category associated with majority of adverse drug reaction, followed by angiotensin. The present evaluation has revealed opportunities or interventions especially or avoidable ADRs which will help in promoting safer drug use, information to the healthcare professionals. Improve the quality of patient care and educate to increase awareness.