NA.

No abstract

I would first like to thank my thesis supervisor, Dr. Neil Segal. Without his knowledge, patience, and guidance, none of the work I accomplished would have been possible. I would also like to thank the other members of my thesis committee, Drs. Don Anderson and Nicole Grosland for their guidance and suggestions with my work. The time required to review and provide suggestions to me was immense and I am grateful for all their help. I would like to thank the students and faculty members in the Orthopaedic Biomechanics Laboratory and Clinical Osteoarthritis Research Program for their help, advice, and support. Finally, I would like to thank my family and friends for their encouragement and support throughout my academic journey. iii TABLE OF CONTENTS LIST OF TABLES .