Maturity-onset diabetes of the young (MODY) is a subgroup of diabetes which is inherited and which could account for 2±5 % of Type II diabetic patients [1]. Information on rare monogenic forms of diabetes could shed light on the development of the more common multigenic varieties of diabetes mellitus.Clinical and metabolic profiles of families with MODY can be diverse [2,3]. Currently, mutations in five genes are known to be associated with MODY and several families with MODY have not been linked to any of the known MODY genes [3±9]. Mutations in genes encoding transcription factors important for normal development and function of pancreatic beta cells have recently become a focus of attention in genetic studies of diabetes mellitus.The aim of this study was to investigate the clinical features and genetic causes of MODY in Iceland.
Subjects and methodsOver 85 % of known diabetic patients have attended the adult and paediatric diabetic clinics at Landspitali, University Hospital, Reykjavik [10,11]. The registers of these services were in-
The original version of this Article contained an error in the spelling of a member of the PRACTICAL Consortium, Manuela Gago-Dominguez, which was incorrectly given as Manuela Gago Dominguez. This has now been corrected in both the PDF and HTML versions of the Article. Furthermore, in the original HTML version of this Article, the order of authors within the author list was incorrect. The PRACTICAL consortium was incorrectly listed after Richard S. Houlston and should have been listed after Nora Pashayan. This error has been corrected in the HTML version of the Article; the PDF version was correct at the time of publication.
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