We report the case of a patient with recurrent pterygo-palatal angiofibroma and its treatment. A 21-year-old male patient had a long history of recurrent epistaxis with progressive nasal obstruction. He was diagnosed with an angiofibroma centered in the right pterygo-palatine fossa. Initially, he underwent surgical excision with removal of the entire tumor. The evolution was clinically good with no signs of recurrence on the cervico-facial scan of control (CT). Nine months after, he presented a reappearance of epistaxis. A cervico-facial MRI was performed and showed a recurrence of the tumor process, which this time was considered inextirpable, hence the decision to opt for radiotherapy with intensity modulated radiation therapy (IMRT). He has improved clinically with a clear reduction in tumor mass on CT scan. This technique represents an interesting alternative to overcome anatomical complexity of the region, cover the tumor and preserve the organs at risk.
Background:
Axial spondyloarthritis (axSpA) is frequent a group of chronic inflammatory disorders that predominantly affects the axial skeleton. It seems to occur more often in males than in females. There are gender differences in clinical presentation of axSpA. Women tend to have milder disease and may therefore be underdiagnosed. Male axSpA patients are more likely to develop radiographic spinal damage.
Materials and Methods:
A cross sectional study was conducted, during the period between January 2012 and December 2017, in a single rheumatology department in Morocco. In total, our study included patients with axial spondyloarthritis fulfilling the Assessment of SpondyloArthritis international Society (ASAS) classification criteria 2010. The data was recorded and compared for both bivariate and multivariate analysis.
Objective:
The aim of our study is to demonstrate the particularities of female axial spondyloarthritis in comparison to the male form.
Results:
In total, 277 patients were included of which 147 were female and 130 were male. In fact, women were older (46 vs 35; p <0.001), had more arthritisis than enthesitis ( respectivally 63.3% vs 36.7% ; p = 0.01 et 59% vs 41%; p = 0.045). There were no significant differences in prevalence of extra-articular manifestations, disease activity (BASDAI) nor BASFI.
Multivariate logistic regression analysis suggested that female sex was associated with a greater age at presentation, (IC: 1,053-1,103, OR=1,07, p<0,001), and arthritis (IC: 2,37-4,26, OR=2,3, p=0.004).
Conclusion :
Comparison between male and female patients suffering from axial spondyloarthritis found differences and similarities in the disease expression. This study showed that women had less severe forms of spondyloarthitis.
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