Plants are the tremendous source for the discovery of new products with medicinal importance in drug development. Today several distinct chemicals derived from plants are important drugs, which are currently used in one or more countries in the world. Secondary metabolites are economically important as drugs, flavor and fragrances, dye and pigments, pesticides, and food additives. Many of the drugs sold today are simple synthetic modifications or copies of the naturally obtained substances. The evolving commercial importance of secondary metabolites has in recent years resulted in a great interest in secondary metabolism, particularly in the possibility of altering the production of bioactive plant metabolites by means of tissue culture technology. Plant cell and tissue culture technologies can be established routinely under sterile conditions from explants, such as plant leaves, stems, roots, and meristems for both the ways for multiplication and extraction of secondary metabolites. In vitro production of secondary metabolite in plant cell suspension cultures has been reported from various medicinal plants, and bioreactors are the key step for their commercial production. Based on this lime light, the present review is aimed to cover phytotherapeutic application and recent advancement for the production of some important plant pharmaceuticals.

Adenanthera pavonina L. syn. Red Sandalwood, (Fabaceae) is an unarmed deciduous tree and its bark is traditionally used for treatment of various disease conditions in gonorrhea, haematuria, ulcers, it is astringent, vulnerary and aphrodisiac in nature. The aim of the present study was to evaluate the qualitative analysis of phytochemicals and antibacterial activity of solvent extracts of Adenanthera pavonina bark. Antimicrobial activity of different solvent extracts of Adenanthera pavonina bark were tested against Gram positive and Gram negative bacterial strains by observing the zone of inhibition. The bacteria used in the study were Pseudomonas aeruginosa, Bacillus subtilis, Enterbacter aerogenes, Staphylococcus epidermidis, and Salmonella typhimurium. Ethanolic and aqueous extracts showed the highest activity against all the tested bacteria. These results were compared with the Zones of inhibition produced by commercially available standard antibiotics .The inhibitory effects of extracts are higher or very close and comparable with the standard antibiotics used.