Introduction: Acute myocardial infarction is very common in Bangladesh. It is one of the most common causes of mortality worldwide. The clinical course is associated with various complications. Materials and Methods: To assess the short-term outcome of acute coronary syndrome we select 100 patients. The study was conducted at the Medicine wards of Khulna Medical College Hospital, Khulna from February’2019 to August’2019. We observed the clinical presentations, ECG findings, echocardiographic findings, short term complications and outcome. Results: We found that most of the patients (61%) were within 45-64 years of age. Chest pain was the most common (85%) presentation. NSTEMI is more common than STEMI. 53% patients developed complications. Acute LVF is the most common (23%) complication. AV block is the most common arrythmia (10%). We found overall mortality 38%. Conclusion: Early detection of complications is essential for reduction of morbidity and mortality. This study will help to evaluate short-term complications and to give appropriate management. Medicine Today 2021 Vol.33(1): 42-44

Abstract

Background: Recent studies have demonstrated the role of several laboratory tests in addition to RT-PCR in the diagnosis of COVID 19. Some of these, laboratory tests are indicators of the current state of the disease, while others have proved to be useful prognostic markers. Objective: The objective of our study was to evaluate the hematological, biochemical and radiological changes in COVID-19 patients. Methods: It was an observational and analytical study done retrospectively. The whole number of patients were included on the basis of inclusion and exclusion creteria. All were confirmed cases of COVID-19 patients either admitted in different hospitals or were in home isolation. Results: Total study cases was 112. Complete blood count revealed, leukocytosis was present in 9 (8.0%) cases and leucopenia in 8 (7.14%) cases. Neutrophilia was present in 27 (24.1%) cases; neutropenia in 9(8.0%) cases, lymphocylosis in 17 (15.2%) cases; lymphopenia in 28 (25%) cases. Neutrophil Lymphocyte ratio (NLR) revealed mean value of NLR 2.3(±1.1) with a range of 0.6-4.0. Decreased total circulating eosinophil count (<40/cmm) was found in 6 (5.3%) cases. Thrombocytopenia was found in 31 (27.7%) cases, Elevated ESR was found in 53 (47.3%) cases; CRP value was increased in 47 (42.0%) cases. Increased serum ferritin was found in 29 (25.9%) cases. D-dimer was increased in 35 (31.3%) cases; Xray chest showed bilateral pneumonia in 26 (23.2%) cases. High resolution computed tomography (HRCT) of chest revealed ground glass opacities in 11(9.8%) cases. Conclusion: Multiple changes in laboratory findings were observed such as altered NLR, elevated acute phase reactants, increased seromarkers (S ferritin, D-dimers) and also opacities in chest imaging. Bang Med J Khulna 2020: 53 : 13-16

Background: Dengue is a very common seasonal public health problem causing significant mortality every year. In 2019 an outbreak occurred in Bangladesh. Few new manifestations and multi organ involvement were found. Objective: The objective of the study was to see the clinical and laboratory manifestations and outcome of dengue fever in a medical college hospital. Methods: It was an observational study in a medical college hospital in Bangladesh. Study period was one year. The patients were confirmed cases of dengue. Apart from detailed clinical history, examination of patient, relevant investigations and follow up was done until discharge. Result: Total number of cases was 98. Out of them 62 (63.2%) were male and 36 (36.73%) were female. Fever was most common (100%) manifestation and duration of fever ranged from 5 to 8 days with a mean duration of 6.3 (± 1.0) days. Among other symptoms generalized body ache was most common (63, 64.3%). Generalized weakness was present in 60 cases (61.2% cases) Bleeding manifestations was present in 41 cases; abdominal manifestations were found in 11 cases. Blood for NSI was positive in 94 (95.9%) cases; most cases (71, 72.4%) became positive between 2nd to 4th day. Ninety (91.9%) cases developed thrombocylopcnia and it started at 5th day in 45 (45.9%) cases. Blood transfusion was given in 12 (12.2%) cases & Platelet transfusion was given in 3 (3.1%) cases. Complete recovery was in 96 (98%) cases and Death occurred in 2 (2.0%) cases. Conclusion: Bleeding was a dominant presentation. Some atypical manifestations like gastro intestinal features were also observed. These findings will help physicians in early diagnosis of dengue. Bang Med J Khulna 2020: 53 : 3-7