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BACKGROUND: There has been a few studies about the predictability of metabolic syndrome (MetS) based on the Framingham risk score (FRS) as a tool for predicting the risk of 10-years cardiovascular diseases (CVD) in Iranian population. The aim of this study was to compare the risk stratification obtained with the FRS and MetS in a cohort of the Iranian population. METHODS:In this population-based study Kerman Coronary Artery Disease Risk study, Iran, MetS was diagnosed as defined by the revised National Cholesterol Education Program definition criteria (ATPIII) and the FRS was calculated using a computer program, previously reported algorithm. RESULTS:Overall, the prevalence 10-years risk of CVD for patients with MetS was significantly different with those without MetS (74.3 vs. 86.4% for low-risk patients, 18.1 vs. 12.3% for intermediate-risk people, and 7.6 vs. 1.3% for high-risk individuals) (P < 0.001). The frequency of intermediate-risk and high-risk for 10-year CVD in men with MetS (39.5 and 18.3%, respectively) was considerably higher than women with MetS (3.2 and 0.1%, respectively). Using multiple logistic regression, the odds ratio of MetS in intermediate-risk and high-risk FRS group was 1.7 and 6.7, respectively (P < 0.001).CONCLUSION: Significant association between the presence of MetS and high risk for CVD based on FRS was revealed in both men and women indicating a good concordance between MetS and FRS in predicting the risk of CVDs. However, the odds ratio of the development of risk of cardiovascular events among women was higher than men with MetS.

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Density functional theory (DFT) calculations have been performed to investigate the properties of the electronic structures of pyrazine-doped boron nitride nanotubes (PD-BNNTs). e structural forms were �rstly optimized and then nuclear magnetic resonance (NMR) parameters have been calculated on the optimized structures. e chemical shielding isotropic (CS I) and chemical shielding anisotropic (CS A) parameters were calculated at the sites of 11 B and 15 N nuclei in structural forms of BNNT including the perfect (a) model and PD-BNNTs (b), (c), and (d) models. e results indicated that the changes are most signi�cant for those nuclei placed in the nearest neighborhood of the pyrazine-doped ring. e changes of the electronic sites of the N atoms are also more signi�cant than those of the B atoms. e di�erence of LUMO-HOMO gap for the perfect model was larger than the PD-BNNTs models. Also the atomic charge distribution of N and B atoms has been determined in nanotubes by natural bond orbital (NBO) analysis. All calculations were performed by the B3LYP method and 6-311G * * basis set using Gaussian 98 package of program.

A computational study on the basis of density functional theory (DFT) calculations has been performed to investigate the properties of the electronic structure of (6,0) zigzag boron nitride nanotubes and two models ((a) and (b)) of diborinin-doped boron nitride nanotubes (DBD-BNNTs). e calculated structural energies yield similar values for two models of DBD-BNNTs. Isotropic (CS ) and anisotropic (CS ) chemical shielding parameters of the optimized BNNT and DBD-BNNTs are calculated. e results illustrate that the changes in chemical shielding tensors of 11 B and 15 N nuclei are more signi�cant in the nearest neighborhood of the diborinin ring due to doping process. e changes of the electronic sites of the N atoms are also more signi�cant than those of the B atoms. e dipole moments of the diborinin-doped BNNT structures show changes with respect to the pristine model. It is clear that the doping of diborinin ring decreases the energy gaps of the pure BNNT. For the pure model, the HOMO is located on the nitrogen atoms, and the LUMO is uniformly distributed throughout the B-N bonds. In contrast, for the diborinin-doped models, the majority of the HOMO and LUMO are located at the diborinin-doped regions.