Background & Aims-Although anti-tumor necrosis factor (TNF) therapy can effectively treat Crohn's disease (CD), there is concern that it might increase the risk of non-Hodgkin's lymphoma (NHL). A meta-analysis was performed to determine the rate of NHL in adult CD patients who have received anti-TNF therapy and to compare this rate with that of a population-based registry and a population of CD patients treated with immunomodulators.

AimsTo assess the numeracy and literacy skills of individuals with Type 1 diabetes and determine if there was a relationship with achieved glycaemic control independent of socio-economic factors. Methods112 patients (mean age 43.8+/-12.5 years, 47% male, mean duration of diabetes 22.0+/-13.2 years) attending Bournemouth Diabetes and Endocrine Centre were randomly selected from the Centre's diabetes register and invited to participate in the study. The Skills for Life Initial Assessments were used to measure numeracy and literacy. These indicate skills levels up to Level 2, equivalent to the national General Certificate of Secondary Education grades A*-C. HbA 1c was also measured.Pearson's correlation was used to measure the correlation of numeracy and literacy scores with HbA 1c. T-tests were used to compare mean HbA 1c between those with or without Level 2 skills and multiple linear regression was used to investigate whether any differences were independent of demographic and socio-economic factors. ResultsLiteracy was not associated with achieved HbA 1c . In contrast, participants with numeracy skills at Level 2 or above achieved a HbA 1c lower than those with numeracy skills below Level 2 (p=0.03). Although higher socio-economic status was associated with lower mean HbA 1c , the relationship between numeracy and HbA 1c appeared to be independent of socio-economic factors.Diabetic Medicine final manuscript 2.12.10 3 ConclusionLow numeracy skills were adversely associated with diabetes control. Assessment of numeracy skills may be relevant to the structure of diabetes education programmes. Word count 228Diabetes UK Abstract reference MARD8558IN

No abstract

No abstract

No abstract