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Introduction: Amongst other problems, dialysis patients also present mental and psychological problems. Objectives: In this study, we investigated the effect of mindfulness-based cognitive therapy (MBCT) on quality of life and self-efficacy in hemodialysis patients. Patients and Methods: In a descriptive study, 50 hemodialysis patients undergoing dialysis in Hajar hospital were randomly selected and divided into two groups of experimental and control. The experimental group attended 2 to 2.5 hours treatment sessions according to the MBCT program. Before the intervention and two months after, the outcomes of the study, regarded as, quality of life and self-efficacy were evaluated using the 36-Item Short Form Health Survey (SF-36) and Sherer et al’s General Self-efficacy Scale, respectively. Data were analyzed using descriptive statistics, independent t test, paired t test, and Wilcoxon test in the Stata software. Results: The results indicated that 2 months after intervention, a decrease of 2.05 points in mean score for quality of life in the control group and an increase of 10.30 points in the intervention group at P<0.01 significance level was detected. Furthermore, mean self-efficacy score increased by 0.95 in control group and 5.2 points in the intervention group at P<0.01 significance level. While, the mean scores for quality of life and self-efficacy increased after intervention, the difference in the mean scores between the two groups was not statistically significant after intervention (P>0.05). Conclusion: The results of this study showed that the MBCT program resulted in an increase in the mean scores for quality of life and self-efficacy in hemodialysis patients.

Introduction: The role of vitamin D in metabolism, bone-mineral regulation, and anti-oxidation effect has drawn researchers’ attention toward its exact role in hemodialysis. Objectives: In this study, the effect of uric acid level reduction on serum 25-hydroxy vitamin D levels in hemodialysis patients was assessed. Patients and Methods: This study is a triple-blind clinical trial conducted on 81 hemodialysis patients suffering from asymptomatic hyperuricemia. Serum uric acid levels were assessed at the start of the study. Then patients were divided randomly into two groups of intervention and control. The intervention group received 100 mg of allopurinol tablets daily for two months. The control group received placebo tablets for the same duration. At the end of the study, 25-hydroxyvitamin D and uric acid levels were assessed. Data were analyzed using SPSS software and chi-square, independent t test, Mann–Whitney U, and Spearman’s rank correlation tests. Results: In our study, two groups of control and intervention were similar in terms of patients’ demographic and hemodialysis characteristics. After the intervention, compared to the control group, the serum uric acid levels were significantly lower in the intervention group, while the level of 25-hydroxyvitamin D showed no significant difference between the two groups. Conclusion: In this study, no significant effect of uric acid lowering therapy with vitamin D elevation in hemodialysis patients was detected. Trial Registration: The trial protocol was approved by the Iranian Registry of Clinical Trials (identifier: IRCT2015041721803N1; https:// en.irct.ir/trial/18996, ethical code#IR.SKUMS.1395.231).

Introduction: The homeostasis of magnesium (Mg) is perturbed in chronic kidney disease. It has been supposed that plasma Mg has a principal role to regulate the secretion of parathyroid hormone (PTH). Plasma Mg is capable of modulating secretion of PTH. Recent investigations showed that low serum Mg levels in patients with kidney disease have been linked to increased mortality. Objectives: The aim of this study was to determine the relationship between serum Mg and PTH levels in hemodialysis patients. Patients and Methods:This cross-sectional study was conducted on 56 hemodialysis patients in hemodialysis center of Hajar hospital of Shahrekord in 2015. Regular hemodialysis patients who had at least three months history of dialysis were enrolled to the study. The serum levels of Mg, calcium, phosphorus, intact PTH (iPTH), alkaline phosphatase, albumin and bicarbonate were measured. Results: In this study, 61.5% of the 52 patients were male. Mean ± standard deviation (SD) of patients' age was 60.5 ± 17.7 years with median of 63 years old. The average duration of dialysis was 44±39.5 months (median 36 months). Additionally the dialysis dose was 517 ± 479 weeks (median; 414 weeks). Mean ± SD of serum iPTH and Mg were 360.1 ± 238.2 pg/mL and 2.2 ± 0.2 mg/mL respectively. In this study we found a significantly positive correlation of iPTH with serum Mg levels (r = 0.28, P = 0.04). Conclusion: This study shows impact of Mg on parathormone secretion. Our findings require further investigations with larger and multicentric studies. Please cite this paper as: Fooladgar M, Malekpour A, Asgari-Savadjani S, Mardani S. Serum magnesium in association with parathyroid hormone levels in routine hemodialysis patients. J Parathyr Dis. 2018;6(1):13-15.

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