No abstract

Chinaldin‐N‐oxid (I) liefert bei der Oxidation mit Thallium‐triacetat oder Bleitetraacetat in Eisessig/Acetanhydrid die Oxidationsprodukte (II)‐(V), die z.Tl. ineinander übergeführt werden können.

-A divergent synthesis of three sulfate derivatives of lamellarin , namely, lamellarin 13-sulfate (2), 20-sulfate (1), and 13,20-disulfate (4) has been achieved via a common intermediate (6) in which 13-OH and 20-OH of the lamellarin core are differentially protected by MOM and benzyl groups, respectively.Compound (6) in turn was prepared using sequential Suzuki-Miyaura coupling of 3,4-dihydroxypyrrole bistriflate (7) as a key reaction.Lamellarins and the related marine pyrrole alkaloids have attracted considerable attention due to their unique structures and highly useful biological activities.

The synthesis of lamellarin α 20‐sulfate, 13‐sulfate, and 13,20‐disulfate is described.