Objective: To find out the frequency of benign and malignant skin adnexal neoplasms. Study design: Descriptive study. Materials and methods: It is a descriptive study in which we studied all cases of skin adnexal tumors that are registered in Mayo hospital over the period of six months. Tumors were evaluated according to the type and site , age and gender of the patient. The tumors are classified by WHO classification. Data collected was analyzed using SPSS Version 21 for statistical analysis. Results:  45 skin adnexal tumors were studied in which, 40 (88.9%) were benign and 5 (11.1%) were malignant. Conclusion: Skin adnexal tumors are comparatively uncommon lesions. Benign neoplasms are more frequent than malignant.

Background: Breast cancer is the most commonly diagnosed malignancy in female population. Aim: To determine and compare the frequency of aggressiveness of breast cancer in pre and post-menopausal patients. Study design: Cross sectional study Place and duration of Study: Department of Histopathology, K.E. Medical University Lahore from 1st January 2016 to 31st December 2018. Methodology: One hundred and fifty female patients diagnosed with breast cancer to assess the aggressiveness of breast cancer in young - premenopausal patients. Post-Surgical Modified Radical Mastectomy specimens were submitted and evaluated for grade, stage, involved lymph nodes, tumor size and metastasis. Results: Sixty four percent of the tumors were left sided and the invasive ductal carcinoma was the most dominant histologic type (96%). Ninety two patients were premenopausal while 58 were post-menopausal. Nodal positivity in patients less than 40 years was more pronounced (74.2% versus 56.8%, p=0.029). Conclusion: Young premenopausal patients represent high risk group for advanced breast cancer. Key words: Breast Cancer, Young, Premenopausal, Post-menopausal, Invasive Ductal Carcinoma

Objective: To examine and to compare c-kit expression in benign and malignant endometrial lesions. Study Design: Comparative, Cross Sectional Study Place and Duration of Study: Department of Pathology, King Edward Medical University Lahore. Methodology: Patients undergoing Gynecological procedures (diagnostic dilatation and curettage or hysterectomies due to dysfunctional uterine bleeding). They were further sub classified into benign and malignant lesions. Patients age and histopathological diagnosis were recorded and described. Conclusion: This study showed, c-kit over expression was seen in 31/68 (45.6%) in endometrial carcinoma and 21/68 (30.9%) in benign endometrial lesions