Among the different sub-branches of poultry farming, turkey breeding is especially attractive due to the intensive production technology and biological characteristics obtained from turkey products. Based on the experience of turkey farming and analysis of the literature, it is obvious that with the development of industrial turkey breeding, a problem arises associated with the pathology of this species of birds, the study of which has not yet been given due attention. To establish the infestation with intestinal parasitic protozoa of young turkeys in the form of the disease Eimeria spp. in 2020 from a specialized turkey breeding farm of the Penza region of Central Russia, samples of feces were examined for the presence of invasive elements. For research coproscopic methods of Fülleborn and Darling were used. Young turkeys of different ages were examined for eimeriosis by the method of intravital coproscopy. On the farm of the Penza region, turkeys were examined from 7 days of age until the full completion of the technological cycle every 14 days by examining at least 20 fresh samples of feces. The study of the dynamics of the invasion of young turkeys with eimeria in the process of the technological cycle of their rearing showed that the greatest infestation of males fell on 35–49 days of age, EI – 30–45%. In young females, the invasion of eimeria was noticeably lower, the peak of infection was at 35–49–63 days of age, EI – 5–30%. The drug Monensin used by us as a coccidiostatic agent in the recommended dose and scheme provided satisfactory efficacy, preventing the clinical manifestation of coccidiosis in young turkeys during the technological cycle of their rearing. Based on the real epizootic situation at poultry farms, it is necessary to carry out comprehensive therapeutic and prophylactic measures against the noted parasitoses, taking into account the exo- and endogenous stages of parasite development.

In addition to positive trends, a lot of problems remain in the modern turkey industry of the country. In the conditions of industrial poultry farming, when a large amount of poultry is contained in a limited area, there is a high risk of parasitic diseases, such as histomonosis, eimeriosis, and cryptosporidiosis. In order to establish an epizootic situation in intestinal parasitic protozoa of young turkeys in the form of diseases: histomonosis (Histomonas meleagridis), cryptosporidiosis (Cryptosporidium baileyi), eimeriosis (Eimeria spp.) Conducted in two specialized turkey farms in Central Russia, the age difference of the same age, the age of the same age. From the floor - for the presence of invasive elements. The results of our research have shown that in industrial poultry farms, young turkeys of different ages are infested with intestinal parasitic protozoa against the background of prescribing coccidiostatics: Eimeria spp. – EI – 5–20%, with a low intensity of invasion; Cryptosporidium baileyi – EI – 10%. In an economy without a clear scheme for prescribing coccidiostatics, infection with Eimeria was EI – 33.3–100%.

A study of the therapeutic efficacy of a new dosage form of eprinomectin – Elivec in case of strongylatosis of the gastrointestinal tract of young cattle was conducted on spontaneously infected animals in the Moscow region. Elivec was administered at a dose of 1 ml per 10 kg of animal body weight, once. The main drug was Ganamectin at the recommended dose subcutaneously once. According to the results of scatoscopious studies, after 10 and 30 days all treated animals were free from invasion. In the production test, the effectiveness of Elivec in relation to the strangulation of the gastrointestinal tract of heifers was: EE – 96.7%, IE – 98.86% and Ganamectin EE – 95%, IE – 98.04%. In the course of research, to differentiate invasive larvae of strongylatosis to the genus, 20 samples of feces from young stock were taken, cultivated in a thermostat at 26°C for 10 days. Strongylatosis larvae differed from each other in the number and shape of intestinal cells, as well as in the size of the larvae and their tail end. Invasive larvae of gastrointestinal strongylatosis belonging to the genus Trichostrongylus, Ostertagia and Bunostomum were found in the studied samples.

The purpose of the work was to clarify the modern epizootic situation on helminthozoonoses of game animals in the Central region of Russia. The material for the study was helminthological collections during 2018–2020 from game animals. Animal carcasses were brought from the territories of the hunting farms of the Vladimir, Moscow, Nizhny Novgorod and Ryazan regions. A total of 218 animal and bird carcasses were studied. 105 heads of 11 species of carnivores (Carnivore) was studied by helminthological methods. One species was studied from the omnivorous animals (Оmnivorae) – boar. Among ruminants (Ruminantia), 54 heads were examined. Helminth fauna of rodents (Rodentia) was studied in 44 heads of 5 species. Three species of birds (Aves) was studied. About 12 species of helminthozoonosis were identified, of which trichinellosis, dirophilariosis, toxocarosis and alveococcosis are particularly hazardous. The main hosts of zoonoses are 7 species of predators. The red fox and some weasels play a leading role in the spread of helminthosis common to humans and animals.

The conducted studies have shown that Eimeria infections are widespread in young turkeys on industrial farms in Russia. The species composition of Eimeria oocysts detected in litter samples of the turkeys kept in the Penza Region showed the following Eimeria species: 80% of Eimeria meleagrimitis, 15% of E. meleagridis and 5% of E. adenoides. The highest Eimeria invasion prevalence in males was determined at the age of 35 days, the IP 45%, and in females at the age of 49 days, the IP 30%. The highest intensity of Eimeria invasion was observed at the same age. Subsequently, we observed a gradual decrease in the prevalence and intensity of Eimeria invasion up to 105 days of age. The clinical manifestations of Eimeria invasion were not observed in the turkeys. The comprehensive measures against exogenous stages (new polycomposite drug Virukill 260) and endogenous stages (eimeriocide, Toltrazuril and probiotic Vetelact) of Eimeria showed high antiparasitic efficacy, and had a positive effect on the biological protection of poultry buildings where young turkeys were grown, and on the economic performance of production. Our results showed the need for a comprehensive control of exogenous and endogenous development stages of Eimeria oocysts on industrial turkey farms.