Introductionreast cancer is the most common type of cancer and the main cause of cancer deaths in women in Iran (1). Although advancements in medical sciences have increased patients' lifespan, the patients are subjected to long-term psychological and physical consequences due to perceiving the disease and its specific therapies as dangerous. Such perception negatively affects the quality of life and psychological well-being of the patients (2). In addition, given the improved survival of breast cancer patients, adaptation to life and management of the disease are among the most important needs of women suffering from the disease (3). Therefore, medical intervention alone is not enough, and it is necessary to design psycho-social interventions for the promotion of health status in these patients (4). Cancer patients are subjected to a profound internal transformation and change in life perspective; therefore, religiosity/spirituality is a matter of central importance for these patients (4-6). In this regard, these patients are strongly seeking to change their lifestyle and increase their spiritual well-being (7). They often request spiritual/religious interventions (8) and believe in the power of religiosity/spirituality to overcome cancer (9). Based on psychoneuroimmunology studies, the consideration of patients' religious/spiritual characteristics in the design of an intervention B

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