Background and Objectives:The organizational commitment of the staff that ensures their continuous and effective presence in the organization is one of the determinants of organizational development. Religion and religious orientation can affect organizational commitment. The purpose of this study was to investigate the correlation between organizational commitment and religious orientation in midwives working in the hospital. Methods:This descriptive-correlational study was conducted in Hamedan in 2015-2016 with 100 midwives working in the hospital who had been enrolled by convenience sampling. The data collection instruments were the Organizational Commitment Questionnaire and the Religious Orientation Scale with confirmed validity and reliability. Data analysis was conducted by the SPSS. Results:The mean scores on organizational commitment, intrinsic religious orientation and extrinsic religious orientation were 136.3±8.07, 39.21±4.25 and 34.44±2.71, respectively. Participants had a high organizational commitment. There was a direct and statistically significant correlation between intrinsic religious orientation and organizational commitment (p=0.01, r=0.15) but not between extrinsic religious orientation and organizational commitment. Conclusion:Given the correlation between organizational commitment and intrinsic religious orientation, it is recommended to use strategies to increase the intrinsic religious orientation of midwives working in the hospital.