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Poor understanding or practice of Total Parenteral Nutrition (TPN) causes devastating complications. Therefore, good Neonatal Intensive Care Unit (NICU) nursing care for preterm neonates and close monitoring of complications is essential for successful TPN therapy. The study was conducted in NICU at Ain Shams University Hospital in Cairo, Egypt, using a quasi-experimental research design with prepost intervention assessments. Data was collected using a self-administered questionnaire sheet and an observation checklist (prepost format) and developed a comprehensive guidelines program about nursing care of TPN of preterm neonates. Results revealed that the program had a significant positive impact on nurses' knowledge and practice outcomes.

Background: Intestinal obstructions are the most common surgical emergencies in the neonatal period. Nurses play an important role in caring of neonates with intestinal obstructions includes pre-operative care and post-operative care. This study aimed to: Assess nurses' knowledge and practices in caring for neonates with intestinal obstruction.

Background: Central Line Associated Blood Stream Infections (CLABSIs) are the most common healthcare associated infections in the Neonatal Intensive Care Unit (NICU). The nurse has an important role in CLABSI bundle during insertion and maintenance. This study aimed to: Assess nursing knowledge and compliance regarding CLABSI bundle. Setting: This study was conducted at the (NICU) in Children University Hospital (Abu Elrish) El-Mounira and New Kasr El-Ani Teaching Hospital. Design: A descriptive design was used. Sample: A purposive sample of 86 nurses included in the study working at the previously mentioned setting. Tools: The first tool is a predesigned questionnaire to assess nurses' knowledge about CLABSI bundle; the second tool was observational checklist to assess nurses' compliance for neonates with CVL. Results: Revealed that less than half had poor knowledge and more tham half had average knowledge about CLABSI bundle while more than half had incompetent practice. Conclusion: The current study provides a picture of the current nursing knowledge and compliance of CLABSI bundle in NICUs. The study conducted that less than half had poor knowledge and less than half had average knowledge about CLABSI bundle while more than half had incompetent practice. In addition, the study illustrated an absence of a uniform protocol for prevention of CLABSI in the studied NICUs and absence of adequate training. This indicates the need for developing a protocol for CLABSI prevention based upon current evidence based guidelines and make education program on this protocol. There is also a need for establishing a system to implement prevention protocols and the monitoring of adherence and CLABSI bundle. Recommendations: Collaboration and continuing education of the staff in the NICUs are vital to improve their knowledge and practices of care provided for neonates with central venous line. Standardized nursing guide lines about CLABSI bundle should be used to guide the nurse while caring of neonate with central line. Make checklist for insertion and maintenance CLABSI bundle for each patient and also make kits for CVL insertion and dressing change.

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