Background: PROM, a condition that occurs when fetal membranes are ruptured at least one hour before onset of labor. While PROM is observed in 10% of all pregnancies, 60-80% of PROM is observed in term and 20-40% in pregnancies less than 37th gestational week. PROM is the most significant reason for preterm labor. The three causes of neonatal death associated with PROM are prematurity, sepsis and pulmonary hypoplasia. Infants born with sepsis have a mortality rate four times higher than those without sepsis. Objective of the study was correlation of blood and gastric culture positive sepsis in PROM newborns. It helps to find out the incidence of PROM in our locality.Methods: This retrospective study enrolled 90 neonates born to healthy mothers with history of PROM more than 18 hours duration, admitted in SNCU/ward at a tertiary care hospital for six months duration from 1st January 2017 to 30 June 2017. Clinical profile of these Newborn with history of PROM was noted such as birth weight, gender, gestation, duration of membrane rupture, history of maternal fever. For all newborns with PROM, sepsis screen had been sent. The neonatal outcome was also recorded, and the data was collected and analyzed by using frequency and percentages.Results: Gram negative bacilli were the commonest cause of neonatal sepsis and male neonates were more prone to infection. PROM and low birth weight especially, ELBW and VLBW are the common high-risk factors for early onset sepsis. Most common organisms isolated in blood and gastric culture were Klebsiella and Staphylococcus aureus respectively.Conclusions: PROM is a high-risk obstetric condition. Active management is needed to enable delivery within 24 hours of PROM as it offers better neonatal outcome. Morbidity and mortality increase as the duration of PROM increases. This can be reduced by early diagnosis, specific treatment and strict infection control practices in neonatal units.

Background: Childhood obesity and hypertension are on the rise and limited data are available regarding the profile of childhood obesity and hypertension from India. We studied the prevalence of childhood obesity and hypertension in a representative sample of school children to find out the relationship between obesity and hypertension in study population.Methods: This prospective, cross-sectional, observational study was conducted in Department of Pediatrics, Shri Vasantrao Naik Government Medical College, Yavatmal, Maharashtra, India and data were collected from urban and rural primary schools of Yavatmal from 1489 children between ages 6-12years, selected randomly. Anthropometric measurements were taken to calculate BMI and blood pressure was taken. Data was analyzed using CDC guidelines and statistically using contingency coefficient. Overweight and obesity were defined by body mass index for gender and age. Gender, age and height were considered for determining hypertension. The hypertensive children were followed up at 3 monthly intervals, 3 times, to look for persistent hypertension.Results: Amongst the 1489 children, prevalence of hypertension was 4.49% and that of pre-hypertension was 1.47% and that of overweight was 1.74% and obese was 0.87%. In girls and boys both, increasing BMI was associated significantly (p<0.0001) with average SBP and average DBP in both pre-hypertension and hypertension groups in rural and urban areas. A higher prevalence of pre-hypertension and hypertension seen in the present study group compared to similar studies in the state. Children with higher BMI were associated with pre-hypertension or hypertension.Conclusions: Prevalence of sustained hypertension overweight and obesity is on rise in children in this part of world. Possible related factors for this current trend may be the increasing sedentary life style, altered eating habits, and increased fat content of diet. The result suggests the need for more public awareness and prevention programs for childhood obesity and hypertension.

Bartter syndrome is rare genetic disorder of kidney characterized by hypokalemia, hypochloremia, metabolic alkalosis, hyponatremia, hypercalciuria, hyperreninemia, hyperaldosteronism with normal blood pressure. Here we report a case of 3 year old girl born of consanguious marriage, with complaints of not gaining weight with history of polyuria, polydipsia, having clinical and laboratory features of Bartter syndrome.