Proptosis is one of the commonest clinical manifestations of pathology involving orbit. Aim of this study is to evaluate causes of proptosis secondary to nasal and paranasal sinus pathology. Prospective study over 2 years. 44 cases of proptosis secondary to nasal and para nasal sinus pathologies studied. There were 63.6% males and 33.4% of females with peak age incidence between 41 and 50 years. Commonest cause of proptosis in our study is malignancy of nose and paranasal sinuses, of which squamous cell carcinoma is common. Frontoethmoid mucocele is the second common cause. Fungal sinusitis account for 15.9% only. To conclude malignancy lesions of nose and para nasal sinuses constitute important cause of proptosis in our study followed by mucocele. Prompt identification of proptosis, a clinical and radiological evaluation is required. The treatment modality has to be decided according to individual lesion.

Background: Otomycosis can be a difficult problem to treat in a patient who already has a perforation of the tympanic membrane. This study highlights the effectiveness of oral Itraconazole in treating such cases.Methods: Thirty-four patients with otomycosis and a perforated tympanic membrane were included in the study and were treated with oral itraconazole and antibiotic ear drops. They were followed up for six weeks to look for treatment response and any recurrence.Results: Of the 34 patients in the study, 25 patients were fully cured with one week of oral Itraconazole therapy. Six out of the remaining 9 patients were cured of the disease with two weeks’ therapy. Three patients needed prolonged treatment and one patient had a recurrence at six weeks.Conclusions: Oral itraconazole therapy is an effective alternative to the traditional methods of treatment for otomycosis with tympanic membrane perforation.

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