Clitoral mass is not commonly encountered in Gynecology practice and the literature is scanty. Clitoral mass can be due to Cancer, Granuloma, epidermoid cyst, peri-clitoral abscess, fibroid and Neuromas 1 and clinical presentation is overlapping making it difficult to diagnose. Clitoral cancer is a form of vulvar cancer, is an unpleasant dreadful malignancy and is very rare. Rare case reports of pyogenic granuloma of the labia and clitoris in postmenopausal women with similar presentation and diagnosed by histopathology requiring excision. Similarly neuromas of clitoris are also a known entity seen mainly after FGM.Aim : Awareness regarding the rare causes of clitoral mass including malignancy and granuloma with their overlapping symptoms.Materials & Methods : Prospective observational case report. Conclusion:A Multidisciplinary approach is important to diagnose and differentiate the clitoris granuloma from that of malignancy. The clinical examination and imaging can be misleading at times and diagnosis is only by histopathology Clinical Significance: Multidisciplinary team involvement and through counseling is needed. Significance of clitoris is well established as the most vital part in sexual function, there is an urgent need to focus our attention on more and more case reports and reviews on its literature of disease related to clitoris.
Aim and Objective To determine the efficacy of antenatal corticosteroids given in the late preterm period. Methodology We conducted a retrospective case–control study on patients with singleton pregnancies who were at a risk of delivering in the late preterm period (34 weeks to 36 weeks 6 days). A total of 126 patients who had received antenatal corticosteroids (prenatal administration of either betamethasone or dexamethasone, minimum one dose) during the late preterm period were taken as cases, and 135 patients who had not received steroids antenatally due to various reasons, for example, who were clinically unstable, presented with active bleeding, non-reassuring foetal status that obligated an imminent delivery and those in active labour were included as controls. The various neonatal outcomes like APGAR score at one and five minutes, incidence of admission and duration of stay in neonatal intensive care unit (NICU), respiratory morbidity, requirement of assisted ventilation, intraventricular haemorrhage (IVH) necrotizing enterocolitis, transient tachypnea of the newborn, respiratory distress syndrome, use of surfactant, neonatal hypoglycaemia, hyperbilirubinemia requiring phototherapy, sepsis and neonatal mortality were compared between the two groups. Results The baseline characteristics of both groups were comparable. There was a lower incidence of admissions to neonatal intensive care unit (NICU) (15% vs. 26%, p = 0.05), respiratory distress syndrome (5% vs. 13%, p = 0.04), requirement of invasive ventilation (0% vs. 4%, p = 0.04) and hyperbilirubinemia requiring phototherapy (24% vs. 39%, p = 0.02) in the babies of the group that received steroids compared to the control group. The rate of overall respiratory morbidity in the neonates was lowered after giving steroids (16% vs. 28%, p = 0.04). The incidence of neonatal necrotizing enterocolitis, hypoglycaemia, IVH, TTN, sepsis and mortality between the two groups was not significant (p > 0.05). Conclusion Antenatal corticosteroids administered to patients between 34 and 36 weeks 6 days of gestation reduce respiratory morbidity, requirement of invasive ventilation, respiratory distress syndrome, hyperbilirubinemia requiring phototherapy and the incidence of NICU admissions in the newborns.
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