Discoloration of urine is not uncommonly encountered in clinical practice and may indicate a significant pathology. However, the majority of instances are benign and occur as the result of trauma to the urological system during procedures or ingestions of substances such as medication or food. This phenomenon is known as the purple urine bag syndrome. It is associated with urinary tract infections occurring in catheterised patients, generally elderly females with significant co-morbidities and constipation. The purple discoloration is most often due to the presence of indigo and indirubin pigments which are the metabolites of tryptophan. In this article, we present a case of elderly man with this rare and interesting phenomenon after insertion of an indwelling catheter. The purple urine disappeared after antibiotic therapy.
Staphylococcal Scalded Skin Syndrome (SSSS) is the medical term used to define a skin condition induced by the exfoliative toxins produced by Staphylococcus aureus. It is also called as Ritter disease, Lyell disease and staphylococcal necrolysis of epidermis. SSSS is most common in children and neonates, and it has been described in adults with renal failure, immunologic deficiency, and other chronic illnesses. The epidermolytic toxin causes loss of cell adhesion in the epidermis causing skin damage.In this article, we present a case of 32 days old male child with dark brown coloured macules all over the body. Based on clinical and paraclinical examinations a diagnosis of Staphylococcal scalded skin syndrome was established which responded favourably to antibiotic treatment, hydro-electrolytic re-equilibration, and adequate local hygiene.
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