Background: Intracranial Pressure of higher than 20 mm of Hg is considered Intracranial Hypertension. For years, Mannitol has been the go-to drug for its cure. However, it has many adverse effects. Therefore, other drugs are being considered for reducing Intracranial Pressure (ICP), and hypertonic saline (HTS) appears to be a good alternative. Methods: The reason for this study is to report any differences in results after using of mannitol or hypertonic saline for treating Intracranial Hypertension (IH) in patients who were in the tertiary care hospital to be treated of moderate or severe Traumatic Brain Injury (TBI). Methodology: All patients who had moderate or severe Traumatic Brain Injury (TBI) i.e, were reported at the hospital and had Glasgow Coma Score lesser than 13, were admitted in the hospital over the course of 2 months of the study will be included. Patients will be randomized into 2 statistically comparable groups. Group A and Group B will be given the standard amount of mannitol and hypertonic saline (3%) and clinical result will be noted for both cases. Results: The results will be calculated by rate of improvement in Glasgow Coma Score (GCS) of both groups and then compared. Primary endpoint will be clinical improvement after 7 days. Conclusion: The rationale behind which drug of the two - mannitol or hypertonic saline solution (HS) - for treatment of people suffering Traumatic Brain Injury (TBI) to be primary varies considerably and there seems to be no protocol to determine which of these should be preferred. Most of the studies that have been done on the topic conclude that Hypertonic saline (HTS) seems to better suited for lowering Intracranial Pressure (ICP), regardless of its concentration. However, other than its apparent superiority in ICP reduction, it doesn’t seem to have any additional benefits, in relation to mortality.
Background: Benign paroxysmal postural vertigo is considered as the most frequent cause of vertigo worldwide because of which various times patient suffers the most dreaded complication which is not just because of vertigo but is due to the loss of balance during activities (such as driving and crossing the road,even while climbing up the stairs) and which is often misdiagnosed as a neurologic condition which further worsen the prognosis. This can be avoided by a simple OPD based manoeuver (series of movements) as a diagnostic procedure in most cases. Once diagnosed another series of movements (manoeuver) can be performed to afford symptomatic relief. Objective: To create a complete systematic review of the prevalent reason of dizziness i.e. benign paroxysmal postural vertigo (BPPV) along with its historic background, diagnostic modality (associated with various manoeuvers ). Also, alternative methods of management considering their success rate and prognosis associated with precautions and primary measures (I.e prevention or decrease of risk factors, precautions and even to educate the patient about the disease. Methodology: This article is reviewed from data taken from various articles found on various search engines like Google Scholars , PubMed , Research Gate along with the data taken from various books on he respective topics. Also, the data searched from various search engines using the terms like BPPV, Vertigo, VOR, Dix - Hallpike Maneuver, Posterior Semicircular Canal, Superior Semicircular Canal. Conclusion : BPPV is a simple disorder that can be misdiagnosed if the history is not taken properly or examination is not done correctly, it can severely affect the patients day to day activity and can be a very problematic condition if the attack is precipitated while activities like driving or crossing the road, or even climbing,which can lead to dreaded complications. Henceforth it is a great topic of concern to resolve this disease which can be usually resolved by a simple OPD based management and can bring a great difference in the patient’s life for GOOD.
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