This research aims to study the causes of neonatal admissions and deaths among newborns at neonate department in Benghazi Children Hospital. A cross sectional retrospective study was conducted during 2019. Data included; causes of admission, causes of deaths, gender, age, residency, area of referral, duration of hospital stay. Out of 1720 neonatal admissions reviewed, the total number of deaths was 229, the overall mortality rate was (13.3%) but much higher (25.2%) among the referred babies. The male gender was predominant admissions and deaths (61.3% and 63% respectively). Most of neonatal admissions and deaths were occurred in the first week of life. The most frequent cause of admission was neonatal jaundice 492 (28.6%) followed by RD 380 (22.1%). The common cause of death was prematurity and its related problems 66 (28.3%), then neonatal sepsis 51 (22.3%) and congenital heart disease 36(15.7%).