Swyer syndrome is caused by abnormal sex differentiation during the embryonic period, resulting in incomplete intrauterine masculinization and undifferentiated gonads. The current case report describes a patient with Swyer syndrome associated with stage 3 gonadal dysgerminoma who has survived for 23 years. At age 18, this patient sought assistance for primary amenorrhea from the Gynecological Services Department of the University of Brasília Hospital. A physical examination revealed that the patient was at Tanner stage 4 with respect to axillary hair, breasts, and pubic hair; she presented with a eutrophic vagina and a small cervix. She was treated with a combination of estrogens and progestogens to induce cycling. Approximately 4 years later, a complex tumor was found and resected; a histopathological analysis revealed that this tumor was a right adnexal dysgerminoma with peritoneal affection. The patient was also subjected to chemotherapy. Her follow-up has continued to the present time, with no signs of tumor recurrence. In conclusion, this report describes an extremely rare case in which Swyer syndrome was associated with ovarian dysgerminoma; relative to similar patients, the described patient has survived for an unusually prolonged time.
Uterine leiomyomas are benign tumors that develop from smooth muscle tissue and are present in up to 77% of women in menacme. They are often asymptomatic but can cause pelvic pain, compression, abnormal uterine bleeding, and degeneration. We present the first case report of a perimenopausal woman who exhibited complete and spontaneous expulsion of uterine fibroids without embolization or use of medication. She complained of a mass extruding from the vaginal orifice associated with bleeding and pain for a couple of hours. The anatomopathological findings showed a myomatous lesion. Complete expulsion of a uterine fibroid is a rare condition that may be associated with profuse hemorrhage and can pose a risk to the patient. When it occurs during perimenopause, it can mimic several clinical conditions. Therefore, gynecologists must remain alert to make the correct diagnosis and treatment.
The new disease COVID-19 is associated with high mortality, as the virus attacks our defences and our immune system. Despite the amount of research by scientists from around the world, currently, no specific antiviral treatment is recommended, and no vaccine is available. However, there is already robust research showing how to improve our immune systems through a balanced diet and lifestyle intervention in order to fight against the virus. We report a series of 10 cases of patients with COVID-19 from a poor community in Brazil who were monitored by telephone due to the lack of resources in the public health system. They received conventional medical drugs and were additionally instructed to change their eating patterns as well their lifestyles. These patients showed favourable results in their illnesses. Lifestyle interventions with balanced nutrition are not antagonistic to traditional medicine. They interact harmoniously to achieve a positive result faster. Although today we know little about the treatment of COVID-19 with drugs, we know a lot about how to improve our immune systems to help our bodies in this battle against COVID-19. Until new treatments and effective vaccines are discovered, perhaps we can revisit the teachings of the father of medicine, who 2500 years ago spoke of the importance of lifestyle interventions such as changes in nutrition, sleep and exercise for the prevention and treatment of diseases.
Objetivo: avaliar a colpocitologia oncótica e a colposcopia no diagnóstico das lesões pré-malígnas cervicais, comparando-as com o estudo histopatológico. Método: foram selecionadas 226 pacientes do ambulatório do Departamento Médico da Câmara dos Deputados (DEMED) para exames simultâneos de citologia e colposcopia. Foram realizadas 117 biópsias em casos com resultados alterados da colposcopia, da colpocitologia ou de ambos. A análise de significância estatística entre os resultados foi estabelecida e foram determinadas sensibilidade, especificidade, valor preditivo negativo e valor preditivo positivo de cada método. Resultados: a citologia diagnosticou 24 de 101 alterações histológicas (23.76%). A especificidade da citologia foi de 96%, a sensibilidade de 23,76%, o valor preditivo
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