Morbidly obese patients present a technical challenge and likely this, and the resultant complications are underestimated. More work needs to be performed to enable suitable allocation of resources.
Patients with a history of multiple invasive SCC should be aware of their increased risk of future NMSC and of melanomas. The results of thisstudy suggest such patients and their care providers should also consider an appropriate screening for internal malignancies.
Congenital is a disease caused by Toxoplasma gondii, an obligate intracellular parasite, which is transmitted via the placenta from mother to fetus. The risk of fetal infection increases with advancing gestation, while the risk of severe fetal disease decreases with gestation. Infection may result in miscarriage, preterm labour or stillbirth. Manifestations in the fetus vary and can include serious and progressive motor, hearing, visual and cognitive issues. Here we report a case of congenital toxoplasmosis detected in the placenta of a preterm infant. The diagnosis of Toxoplasma placentitis was based on the presence of a characteristic true Toxoplasma cyst in the chorionic plate, associated with non-specific features of low grade chronic villitis with multinucleated giant cells, chronic chorioamnionitis and chronic deciduitis. The sensitivity of diagnosis of toxoplasmosis on placental examination is generally low (91% in symptomatic cases). However, given the characteristic morphology of the Toxoplasma cyst and the clinical history of severe fetal brain abnormalities on antenatal imaging, the features were considered in keeping with Toxoplasma placentitis. The histology findings were communicated to the Neonatal Intensive Care Unit. Toxoplasma PCR was subsequently performed on blood and CSF samples from the baby, confirming the diagnosis of congenital toxoplasmosis.
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