Patient blood management (PBM) strategies are needed in the neonate and paediatric population, given that haemoglobin thresholds used are often higher than recommended by evidence, with exposure of children to potential complications without meaningful benefit. A literature review was performed on the following topics: evidence-based transfusions of blood components and pharmaceutical agents. Other topics reviewed included perioperative coagulation assessment and perioperative PBM. The Transfusion and Anaemia Expertise Initiative (TAXI) consortium published a consensus statement addressing haemoglobin (Hb) transfusion threshold in multiple subsets of patients. A multicentre trial (PlaNeT-2) reported a higher risk of bleeding and death or serious new bleeding among infants who received platelet transfusion at a higher (50 000/μl) compared to a lower (25 000/μl) threshold. Recent data support the use of a restrictive transfusion threshold of 25 000/μl for prophylactic platelet transfusions in preterm neonates. The TAXI-CAB consortium mentioned that in critically ill paediatric patients undergoing invasive procedures outside of the operating room, platelet transfusion might be considered when the platelet count is less than or equal to 20 000/μl and there is no benefit of platelet transfusion when the platelet count is more than 50 000/μl. There are limited controlled studies in paediatric and neonatal population regarding plasma transfusion. Blood conservation strategies to minimise allogenic blood exposure are essential to positive patient outcomes neonatal and paediatric transfusion practices have changed significantly in recent years since randomised controlled trials were published to guide practice. Additional studies are needed in order to provide practice change recommendations.
Trans* communities across the United States are under assault. Researchers seeking to work with trans* people and other multiply marginalized and underrepresented communities must attend to ethical research practices within the communities in which they participate. Digital research ethics is particularly murky with issues of embodiment, vulnerability, and unclear IRB guidance. Comparing two transparency activist organizations-Wikileaks and DDoSecrets-we introduce "qubit ethics," a trans*material, transcorporeal ethics of care as praxis within vulnerable online communities. We then demonstrate how this unique approach to research design allows for the complex entanglements that is trans* life, particularly digital life. Finally, we present clear take-aways for qubit-ethics informed social justice research. CCS CONCEPTS• B7; Social and professional topics → User characteristics; Gender.
Previous research has recognized the neoliberal trends that permeate the rhetorics of academic wellness, placing the responsibility for wellbeing on individuals rather than institutions and systems. In this study, the authors implemented a participatory action research (PAR) project to collaborate with different stakeholders in one university writing program and develop programmatic approaches to support the wellbeing one subset of academic faculty: graduate student instructors. Along with an account of how we adapted our PAR methodology to align with the wellness needs of our participants, we also provide a description and analysis of the intervention developed collaboratively in the PAR group. We end with five takeaways that researchers and stakeholders in graduate student education can apply to developing programmatic interventions that better support graduate instructor wellbeing: 1) research methodologies should adapt to foreground wellbeing; 2) productive conversations about wellbeing should start by acknowledging and validating the lived experience of graduate instructors; 3) students want to be involved in programmatic processes and procedures that support their wellbeing; 4) facilitating (but not requiring) non-productive social interaction among grad students can support GI wellbeing; 5) the work of supporting wellbeing is never fully done---we call on administrators, faculty members, and students to continue this work.
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