Skin tumors comprise the largest group of malignancies of the head. Despite the accessibility of such lesions, the treatment of neglected, far advanced cancers, many of which have extended deeply into the facial bones and skull, is often required. The key to the cure of malignant tumors of the head is an accurate diagnosis and evaluation of the margins of an excised tumor. Reconstructive surgery of the head after resection of tumors requires a complete understanding of the anatomy of this region. From January 1986 to December of 2005, 31 patients underwent reconstructive surgery for nonmelanoma skin tumors involving the craniofacial region. Preoperative evaluation of the patients was performed in all cases. The results were estimated from the oncologic and functional point of view. The reconstruction, which was performed, included local, regional, and free flaps. In our series, the 5-year disease-free survival rate was 87%. The primary goal of surgical treatment of skin tumors with invasion of craniofacial bone structure is three-dimensional tumor resection with histologically clear margins. This goal has to be balanced, however, with an acceptable functional and aesthetic result. Resections are planned according to pathologic considerations rather than according to the anatomy involved.

We introduce a methodology to estimate common real estate returns and cycles across public and private real estate markets. We first place REIT indices and direct real estate-NCREIF appraisal-based and transaction-based indices (NPI and NTBI)-on a comparable basis by adjusting for leverage and sector. We extract a common real estate factor, which is allowed to be persistent, from all these markets. Individual real estate indices load on this common factor and they also are driven by persistent, idiosyncratic shocks. The common real estate factor is procyclical and has low correlations with standard systematic factors. Short-run idiosyncratic deviations from the common real estate factor load on several capital market factors for REITs and on liquidity factors for direct real estate.

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Much like their Earth-based counterparts, the requirements of future space habitat structures can be defined by their ability to protect their occupants and provide usable space to live and work in an extreme, isolated environment. Due to the high cost of transporting resources off of Earth's surface, recent efforts focus on developing increasingly Earth-independent structural designs. These new designs use local regolith-based materials as a possible solution for long-term extraterrestrial sustainability. With a focus on an Earth-independent habitat, this research looks at architectures that use spherical regolith-based concrete shells with carbon fiber polymer reinforcement. The research approach is to formulate the structural design problem as a multi-objective optimization of the habitat shell. The objectives that apply to the shell geometry and cross section include the minimization of transportation and construction costs, and the minimization of the probability of loss due to radiation and micrometeorite events. Direct trade-offs arise. The multiobjective optimization applies Pareto optimization to determine which design elements or options afford the greatest effectiveness or efficiency. The authors examine candidate design solutions based on priorities and performance thresholds which indicate that ISRU-based reinforced concrete may be a valuable future investment. While the cases presented here are limited to lunar surface systems, both the general architectures and the methodology for analysis and design are applicable to future Mars settlements.