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COVID-19 highlights nurses' vulnerability as backbone to health services worldwide .This pandemic disease has resulted in remarkable challenges of nursing research and practice worldwide. During this period, two key aspects became apparent: the value of a highly trained clinical care nurse and the importance of research to understand the disease and identify effective treatments. Challenges facing nursing in research include: Obtaining informed consent from patients, conducting research during COVID 19, the wearing of personal protective equipment, impairing communication, and ethics. In nursing practice these challenges include ineffective communications, discrimination, inadequate knowledge, deficient practical skills, social distancing between nursing students, the experience, moving forward, support the transition of new nurses, protect nursing students and new graduates, balance between theory and practice, blended learning, cultural competence.

Work-Related shoulder impingement syndrome is categorized by shoulder pain that is exacerbated with arm elevation or overhead activities. Management options for work-related shoulder impingement syndrome include rehabilitation. Therapeutic exercise was the well-investigated form of rehabilitation. The therapeutic exercise programs consisted of stretching and strengthening the rotator cuff and scapular muscles. The aim of this study was to examine the effect of nursing intervention guide to functional abilities and range of motion of clients with work-related shoulder impingement syndrome. Design: A quasi experimental research design was used. The study was conducted in the Physiotherapy Department, Menoufia University Hospital. Sample: A purposive sample of 40 adult clients diagnosed with shoulder impingement syndrome was included and randomly divided into two equal groups; 20 clients for each group. Instruments: Four instruments were utilized for data collection. A structured interview questionnaire, University of California-Los Angeles shoulder scale, Range of motion measurement scale and Oxford scale. Results: the majority of both study and control groups (80.0% and 100.0% respectively) were unable to use there arm pre nursing intervention, while after three months, 75.0% of the study group improved and became able to function normally compared to the control group. There was a significant improvement in the mean range of motions for shoulder among the study group after three months of the exercise program compared to the control group. Conclusion: Implementation of the nursing intervention guide for the study group was effective in improving functional activities and range of motion compared to control group. Recommendation: Nursing intervention guide about the effectiveness of physical activity and exercise should be part of occupational nurses' role for clients with Work-related shoulder impingement syndrome.

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