The reaction of o -benzoquinone derived by the oxidation of catechols (1a-c) with some nucleophiles containing thiol group (2a-f) has been studied in various conditions, such as pH, nucleophile concentration, and scan rate, using cyclic voltammetry. In various conditions, based on an EC electrochemical mechanism ("E" represents an electron transfer at the electrode surface and "C" represents a homogeneous chemical reaction), the observed homogeneous rate constants (k o bs ) were estimated by comparison of the experimental cyclic voltammetric responses with the digital simulated results for each of the nucleophile. The results show that the magnitude of k o bs is dependent on the nature of the substituted group on the catechol ring and nucleophilicity of nucleophile. C 2009 Wiley Periodicals, Inc. Int J Chem Kinet 41: 426

Electrochemical oxidation of catechol 1a and 4-tert-butylcatechol 1b has been studied in the presence of 1-methyl-1H-imidazole-2-thiol 3 as nucleophile in aqueous solution, using cyclic voltammetry and controlled-potential coulometry. The results indicate the participation of catechol 1a and 4-tert-butylcatechol 1b in Michael reaction with 3 to form the corresponding catechol thioethers 6a and 4b. Based on the observed EC mechanism, the homogeneous rate constants were estimated by comparing the experimental cyclic voltammetric responses with digital simulated results.