Introduction Fibromyalgia is a chronic health condition characterized by widespread, severe musculoskeletal pain that affects an estimated 5–7% of the global population. Due to the highly comorbid nature of fibromyalgia, patients with the disorder often respond poorly to traditional pain treatments. Recent studies suggest that patient response may be more favorable to alternative analgesics, such as cannabis. However, the therapeutic potential of cannabis-based pain treatment for fibromyalgia remains unclear. The present study examined the most recent cannabis literature (2015–2019) and provides a critical review of current research on the safety and efficacy of medical cannabis treatments for fibromyalgia. Methods We followed Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines in searching the PubMed and Medline databases using the search terms “cannabis + fibromyalgia” and then “cannabinoids + fibromyalgia.” Inclusion criteria were a) English language, b) published in peer review journals, c) published from 2015 to 2019, d) all study designs except for systematic reviews and meta-analyses, and e) all cannabis preparations. Results The search identified five applicable studies involving 827 participants that used six different treatments. Review suggested several methodological problems pertaining to generalizability and validity. Conclusion Although the critically reviewed studies superficially suggest that medical cannabis is a safe and effective treatment for fibromyalgia pain, serious methodological limitations prevent a definitive conclusion regarding the use of cannabinoids for pain management in fibromyalgia patients at this time.

Climate change and modern slavery are two of the most significant human rights crises of our time. Women and children are disproportionately vulnerable to such crises, which are intensified under inequitable social conditions and driven by structural barriers to female equality. No research has yet looked at the complex relationship between climate crisis, structural gender inequality, human insecurity, and vulnerability to modern slavery. Our research examined the relationship between environmental stressors associated with climate change, selected structural inequalities, and the estimated prevalence of modern slavery cases across 180 countries. Regression analysis revealed significant results. These findings suggest that indicators of poor environmental health may exacerbate structural social inequalities and increase women’s risk of falling victim to modern slavery. Results showed that women’s share of seats in parliament, education for women, tree cover loss, agricultural management, and air quality assumed more substantial roles in this prediction. Awareness of the unique relationship between environmental indicators of climate change, gender inequality, and modern slavery provides a meaningful contribution to our understanding of factors driving human exploitation. Additionally, we propose a gender analysis of environmental stressors to address both the climate crisis and structural inequalities that increases female vulnerability to insecurity.

Abstract. Modern slavery is a significant global human rights crisis that disproportionately affects women and girls, and research indicates that the COVID-19 pandemic has exacerbated existing vulnerabilities to exploitation. Early evidence suggests that the pandemic has disproportionately affected women and girls, including an increase in lack of access to family planning and adequate sexual and reproductive care and an increase in maternal mortality rates. Additionally, the pandemic has instigated a reduction in economic opportunities and access to education for women and girls and increased violence against women. For this study, regression analysis was used to examine country-level data from 197 UN member countries. Predictor variables included indicators reflecting key areas addressed by UN Sustainable Development Goal 5 (SDG-5): gender inequality, educational and economic opportunities for females, women's leadership, gendered violence, and women's health. SDG-5 calls for gender equality and empowerment of women and girls. The criterion variable was the estimated prevalence of modern slavery across UN countries. Regression analysis revealed significant results across all models. Literacy rates and expected years of schooling for females, femicide, lifetime prevalence of violence, and several indicators of women's health were found to be strongly and significantly related to increased estimated prevalence of modern slavery. Furthermore, we propose that the pandemic has increased vulnerability to exploitation for women and girls by regressing progress across all areas addressed by SDG-5.

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