Purpose: This study was to evaluate effectiveness of I-BiT system for treatment of amblyopia in comparison with standard patching of dominant eye.Methods: This was a prospective randomized comparative study conducted on cooperative amblyopic patients up to 20 years attending outpatient clinic of Mansoura University, Ophthalmic Center. All cases were exposed to full history taking, ophthalmic history, ocular examination which included assessment of visual acuity, slit lamp biomicroscopy, in addition to, Worth 4 Dot Test and Lang test.Results: there was a statistically significant improvement in the (BCVA) (p <0.001) of both groups after 6 months of treatment. There was a statistically significant improvement of Worth 4 dot test results with increased fusion in the cases of both groups. There was a statistically significant improvement of Lang test and achieving positive results in the cases of group 1(29.4% of cases) and group 2 (10.5% of cases) at 6 months of treatment as compared with the pretreatment data.Conclusion: I-BiT system can give equal results to patching of sound eye in treating cases of moderate amblyopia but in a new, simple and joyful way.