Objective: Platelet count has been proposed as a screening test for generalized coagulopathy in women with preeclampsia We performed this study to determine the relationship between platelet counts and the risk of abnormal coagulation and adverse maternal outcomes in women with preeclampsia Methods:We used data from women in the PIERS (Pre-eclampsia Integrated Estimate of RiSk) database Abnormal coagulation was de ned as either an international normalized ratio result greater than and/or a serum brinogen level less than the BC Women's Hospital laboratory's pregnancy-speci c normal range The relationship between platelet counts and adverse maternal outcomes was explored using a logistic regression analysis The sensitivity, speci city, positive predictive value, and negative predictive value of platelet counts in identifying abnormal coagulation or adverse maternal outcomes were calculatedReslts: Abnormal coagulation occurred in 105 of 1405 eligible women (75%) The odds of having abnormal coagulation were increased for women with platelet counts < 50 × 10 9 /L (OR 778; 95% CI 336 to 1803) and between 50 and 99 × 10 9 /L (OR 269; 95% CI 144 to 501) compared with women who had platelet counts above 150 × 10 9 /L Platelet counts < 100 × 10 9 /L were associated with signi cantly increased odds of adverse maternal outcomes, most speci cally blood transfusion A platelet count of < 100 × 10 9 /L had good speci city in identifying abnormal coagulation and adverse maternal outcomes (92% [95% CI 91% to 94%] and 92% [95% CI 91% to 94%], respectively), but poor sensitivity (22% [95% CI 15% to 31%] and 16% [95% CI 11% to 23%], respectively) Conclsion: A platelet count < 100 × 10 9 /L is associated with an increased risk of abnormal coagulation and maternal adverse outcomes in women with preeclampsia However, the platelet count should not be used in isolation to guide care because of its poor sensitivity Whether or not a platelet count is normal should not be used to determine whether further coagulation tests are needed Résltats : Une coagulation anormale s'est manifestée chez 105 des 1 405 femmes admissibles (7,5 %) Les risques de présenter une coagulation anormale étaient accrus chez les femmes qui comptaient des numérations plaquettaires < 50 × 10 9 /l (RC,7,78; IC à 95 %,3,03) The Role of Platelet Conts in the Assessment of Inpatient Women With Preeclampsia avec les femmes qui comptaient des numérations plaquettaires se situant au-delà de 150 × 10 9 /l Les numérations plaquettaires < 100 × 10 9 /l ont été associées à une hausse signi cative des risques de connaître des issues maternelles indésirables, plus particulièrement une transfusion sanguine Une numération plaquettaire < 100 × 10 9 /l présentait une bonne spéci cité pour ce qui est de l'identi cation d

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