Purpose:  To evaluate the effect of intravitreal Aflibercept injection on wet AMD both functionally and anatomically after loading doses. The secondary aim is to evaluate the effect of risk factors including (gender, age, smoking, hypertension, and diabetes meatus) on the patient’s response. Study Design:  Interventional case series. Place and Duration of Study:  Al-Haitham Eyes Teaching Hospital in Baghdad, Iraq, from November 2021 and September 2022. Methods:  Fifty eyes of 47 patients with treatment naïve wet AMD were selected through convenient sampling. Data were collected for age, gender, smoking, and chronic disease. Clinical examination, best corrected visual acuity (BCVA), optical coherence tomography angiography, and spectral domain optical coherence tomography SD-OCT were performed at baseline and then at 16 weeks, after three one-monthly injections of Aflibercept 2 mg/ 0.05 ml intravitreally. Results:  Mean age was 68.23 ± 8.5 years. Mean difference in BCVA was 0.37 ± 0.03 (P = 0.000) and mean difference in central macular thickness was 105.72 ± 45.05 (P value < .0000) at 16 weeks. CNV was associated with intra-retinal fluid in 52% of cases, subretinal fluid in 72%, pigment epithelial detachment in 20%, intraretinal hemorrhage in 6% and subretinal hemorrhage in 4%. Studying associations between the responses of Aflibercept with the general features of the patients as age, gender, chronic diseases and smoking status, revealed no statistically significant difference. Conclusion:  This study demonstrates that aflibercept is effective for the treatment of patients with wet AMD both functionally and anatomically after the loading doses. The presence of intraretinal fluid at presentation had a negative effect on the vision.

During our work in dental clinic we recorded an issue which is very public and serious at the same time. The ignorance of mothers in the field of dental knowledge lead to massive problems in childhood that ends in loosing even permanent teeth not only primary early. In addition to irrational drug use for children instead of seeking dental care. Patients and method-63 women agreed to fill the questionnaire and accepted the follow up. Questionnaire was prepared to fulfil the dental and pharmacological fields of the study. Data were collected, analyzed and discussed. Results-Iraqi women were ignored completely because of war and the situation after fall of Baghdad 2003. Before that time informed organized programs were held to increase level of knowledge of people concerning general and dental health besides awareness and legislations concerning drugs selling in pharmacies. Nowadays these are all passed over and high percentage of women are ruled by families' law, this affects the level of rising up children in turn since many of the lose their chance to complete education.