Objectives:To evaluate the effect of half adult dose of oral Rifampicin on mean change in best corrected visual acuity and central macular thickness in patients with central serous chorioretinopathy.Methods:Thirty-eight eyes of 31 patients with idiopathic central serous chorioretinopathy (CSCR) were registered. Unaided Visual acuity, best corrected visual acuity was documented and detailed slit lamp examination along with dilated ophthalmoscopy was performed. All subjects were treated with oral Rifampicin 300 mg (half adult dose) daily for 03 months. Patients underwent a complete ocular and systemic examination as well as central macular thickness (CMT) measurement by optical coherence tomography (OCT) every month after starting treatment until four months. Fundus fluorescein angiography (FFA) was performed in recurrent cases. Liver function tests were carried out prior to the treatment and during follow up period.Results:A total of 38 eyes of 31 patients (24 males, 07 females) were included in the study. Mean age of patients was 36.16±3.19 years (range 30-44). Mean best corrected visual acuity (BCVA) before treatment was 0.56±0.11 and improved to 0.47±0.14 at 04 weeks (P<0.001) of treatment. The mean CMT at the time of presentation was 494.39±96.29 um and was decreased to 306.90±50.71 um after 04 weeks of treatment (P<0.001). The mean induced reduction in CMT was 187.48±122 um (P<0.001) while that in BCVA 0.41±0.16 at 04 weeks of treatment (P<0.001). Liver function tests were within normal range before and after the treatment.Conclusion:Half adult dose rifampicin (300mg) is effective and safe in treatment of central serous chorioretinopathy without causing any systemic imbalance.

Background and objectiveSquint surgery is frequently performed successfully in Hyderabad. However, no study in any detail has been performed on the outcome of monocular surgery for horizontal squint in the region. This study aims to determine the results of monocular surgery for horizontal trabismus.DesignRetrospective/observational study.Subjects and methodsThe study was conducted on patients aged under 45 years, presenting with horizontal strabismus and undergoing monocular squint surgery. Anterior segment slit lamp examination, and if possible, posterior segment examination with 90 diopter (D) and 78 D fundoscopes was performed. Angle of deviation was measured. Patients were divided into two groups (esotropia and exotropia). Investigations were performed. Surgery was done under general anesthesia. A second surgical procedure was performed after six months for any residual deviations.ResultsAfter squint surgery, patients in group 1 (79%) and in group 2 (73.3%) had residual deviation of less than 15 prism diopters (PD). The preoperative deviations of 60 PD or less illustrated excellent domino effects with residual deviation of fewer than 15 PD. Three patients with successive deviation underwent a second surgery with excellent outcomes.ConclusionFew extraocular muscles can be prevented due to monocular squint surgery when multiple surgeries are needed.

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A case of 46-year-old male is presented who came with complaints of painless, progressive deterioration of vision in both eyes and he was using Latanoprost and Cosopt eye drops in both eyes. His visual acuity was 6/60 in right eye and perception of light in left eye. The intraocular pressures were 28 mm Hg (OD) and 18 mm Hg (OS). There was iridocorneal adhesion and posterior embryotoxon in his right eye and leucoma in left eye. Cup-disc ratio was 0.7. He had hypodontia, midface hypoplasia, hypertelorism, and telecanthus. Family history was also positive. His sister also had iris stromal hypoplasia along with posterior embryotoxon. A diagnosis of Axenfeld Rieger Syndrome was made The patient underwent glaucoma drainage devise (AGV) surgery in his right eye. Post operative pressures were 10mm Hg. He was later referred to maxillofacial surgeon, cardiologist and counseled for avoiding cross marriages to prevent this inherited disease