Developing environmentally acceptable and reliable nanoparticle production technologies is a crucial step in nanotechnology. Because of their unique chemical, physical and biological properties, AgNPs have the potential to be used in various ways. As potential agents, biomolecules got from a variety of plant components were used to make it. Despite many academic efforts in the previous decade, synthesizing stability with greater applicability remains a serious challenge. This review reviewed the most recent advancements and breakthroughs in the manufacture of biogenic AgNPs, as well as their potential uses.

Background: P.aeruginosa, has been frequently connected to immune-compromised individuals. Dynamic electrochemical metabolite assists in the creation of biofilms, the production of genes, and the maintenance of bacterial cells. The bacteria produce several phenazine derivatives, as well as the blue-green pigment pyocyanin, which works as a signalling molecule in quorum signalling and virulence factors. Objective: This review paper intends to give information on the compound's history, virulence mechanism, current biological horizon opened, as well as antagonism and bio-control actions in other bacteria. Current industrial trends and the prospects of pyocyanin-based development were also analysed. Methods: A bibliographic search of scientific literature published up to 2020 was conducted using scientific databases and search engines. Pyocyanin, phenazine, Pseudomonas, virulence, quorum signalling, health, in vivo, and clinical investigations were among the keywords used in various combinations. The data were retrieved independently from eligible papers using the usual data extraction approach. Results: Due to pyocyanin's antibacterial properties, the pharmaceutical industry is predicted to grow faster than other businesses. P.aeruginosa which has had its respiratory chain altered by protonated 3,5-dichlorophenol in water can be used as a biosensor. Cellular systems exposed to the chemical experience increased oxidative stress, which leads to gradual apoptosis. Pyocyanin is engaged in bacterial signalling processes, influencing colony shape and alarming innate immune cells. Conclusion: Focused research on the virulence factor is required, as the specific contribution remains unknown. The link between biological and therapeutic features needed well description to determine the precise action mechanism(s) to design novel medications.

No abstract

No abstract