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Objectives: Oral Squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral cavity. The study was done with the aim to determine the clinical pattern of OSCC seen in tertiary care hospital of Karachi, Pakistan. The frequency of neck metastasis in different staging of squamous cell carcinoma was also recorded. Study Design: Retrospective study. Setting: Department of Oral & Maxillofacial Surgery Liaquat College of Medicine and Dentistry. Period: June 2013- July 2016. Material & Methods: It included 35 males and 25 females which presented with different sites and stage of squamous cell carcinoma. Clinically patients were staged as stage I, stage II, stage III and stage IV and comprised of 3, 8, 30 & 19 patients respectively. Patients presented with cancer of buccal mucosa (31 patients), retromolar region (12 patients), maxillary alveolus (8 patients), tongue (2 patients), floor of mouth (4 patients) & lip (3 patients). Right side was most common, 48 patients as compare to left side, 12 patients while lip cancers was in upper lip in all patients including commissure. Results: Total 60 patients were included in the study with the male to female ratio of 1.4:1. No significant association was seen between age and gender of the patient (p-value 0.933). Majority of patients were male involving buccal mucosa (51.67%) as the most frequently involved site followed by retromolar area (20%) and tongue (13.3%). Mean age of patients included in the study was 50.87 ± 5.53. Conclusion: Most of the cases of OSCC were seen in older patients with increased number of cases involving buccal mucosa as their primary site. Majority of the tumors were classified as stage III followed by Stage IV, Stage II and stage 1 respectively.

Objective: To determine dentist’s perspective regarding NHS guidelines for prophylactic removal of Impacted Third molars among dentists of Karachi. Study Design and Setting: It was a cross sectional study design based on the questionnaire. Questionnaire was filled by total 110 general dentists selected by random sampling and was practicing in various private and government setups of Karachi to know about their preference regarding prophylactic removal of asymptomatic third molar. Methodology:The questionnaire comprised of total 13 questions to find out dentists view point about the prophylactic removal of impacted third molar. The results were then analyzed using SPSS version 23. Frequencies, percentages of different variables used in the study were calculated to identify the co-relation among different attributes. P-value of less than or equal to 0.05 was considered statistically significant. Results:The study reflected that 71.8% dentists were aware with the NHS Guidelines for removal of asymptomatic & impacted third molars while 28.2% dentists preferred conventional approach. The study also revealed Mesioangular impaction as being the most commonly observed type of impaction in the dental practice. Conclusion: It was concluded from this study that majority of dentists were aware of the guidelines provided by NHS and regarding the angulation of impacted teeth most of the impactions seen at the dental office were Mesioangular.

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