India has a rich heritage of knowledge on plant-based drugs for use in preventive and curative medicines. Among those mangrove plants have been used in folklore medicines and extracts from mangrove species have proven inhibitory and curative activity against different diseases including Anti-oxidant, Anti-viral, Anti-diabetic, Anti-cancer, Anti-microbial, Anti-inflammatory, Anti-ulcer activity. Along with different pharmacological activities this review also summarizes mangrove role in the prevention of soil erosion along with it plays a major role in curing Baldness.