Pd(MME)Cl2 complex (MME = methionine methyl ester) was synthesised and characterized by physicochemical measurements. The reaction of [Pd(MME)(H2O)2]2+ with amino acids, peptides, or dicarboxylic acids was investigated at 25°C and 0.1 M ionic strength. Amino acids and dicarboxylic acids form 1 : 1 complexes. Peptides form both 1 : 1 complexes and the corresponding deprotonated amide species. The stability of the complexes formed was determined and the binding centres of the ligands were assigned. Effect of solvent on the stability constant of Pd(MME)-CBDCA complex, taken as a representative example, shows that the complex is more favoured in a medium of low dielectric constant. The concentration distribution diagrams of the complexes were evaluated.

0 0.5 1 1.5 450 350 250 Wavenumber (nm) Absorbance B D A C Electronic spectra of [Pd(MME) (H 2 O) 2 ] 2+ and its uracil complexes Speciation of mono-and binuclear Pd(II) complexes involving mixed nitrogen-sulfur donor ligand is investigated; 4,4′-bipiperidine is used as a linker.Pd(MME)Cl 2 complex, where MME = methionine methyl ester, was synthesized and characterized by elemental analysis and spectroscopic techniques. [Pd(MME)(H 2 O) 2 ] 2+ interacts with some DNA constituents giving 1 : 1 and 1 : 2 complexes. The binuclear complexes having 4,4′-bipiperidine as a linker and involving [Pd(MME)(H 2 O) 2 ] 2+ and DNA constituents were investigated. The results show formation of [(H 2 O)(MME)Pd(Bip)Pd(MME)(H 2 O)] 4+ . Inosine, uracil, and thymine interact with the previously mentioned complex by substitution of the two coordinated water molecules. Formation constants of all possible mono-and binuclear complexes were determined and their speciation diagrams were evaluated.