Electronic cigarettes (e-cigarettes) use has increased rapidly since their introduction. 1,2 Vaping is now the most popular alternative to smoking among younger populations in the United States. 3,4 In the last decade, e-cigarette use among young people has increased mainly in high-income countries, 5,6 and use in past and current cigarette smokers is also highest in these countries. 7 Australia has relatively low rates of e-cigarette use compared to other high-income countries, [8][9][10][11][12] which is likely a result of differences in regulation and access.Evidence of the safety of e-cigarettes is mixed and further complicated by differences in the benefits and harms as a smoking cessation intervention relative to recreational use among non-smokers.The perception that e-cigarettes are less harmful than cigarettes 13,14 justifies their use as a smoking cessation intervention from a harm reduction perspective. 15 However, the short-term and long-term health effects of e-cigarettes are not yet well understood. 16,17 Emerging evidence has suggested a link between flavoured e-cigarette use and cardiovascular diseases, 18 and vaping products containing tetrahydrocannabinol may have played a role in vaping-related lung injuries
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