No abstract

Objective: To determine the frequency of stillbirths in obese pregnant women. Design of the Study: It’s a descriptive cross-sectional study. Study Settings: This study was carried out at Department of Obstetrics and Gynecology, Lady Reading Hospital Peshawar from January 2018 to July 2018. Material and Methods: In this study a total of 289 patients were observed. Detailed history was taken from each patient, period of gestation was calculated from 1st trimester scan, conducted by a person having at least 2 years post-graduate training experience in his/her respective field. Height/Weight measurements were done by the same standardized equipment’s for all enrolled patients and BMI calculation done by standard WHO formula before delivery. Baby after delivery was examined and looked for presence/absence of vital signs by the designated obstetrician. Outcome of pregnancy either alive or stillborn baby was recorded for each patient in order to fulfill the objective of study. To control bias and confounding, exclusion criteria had strictly followed. All the data was recorded on a pre-designed Proforma and subjected to analysis. Results of the Study: Our study shows that mean age of 28.87 +3.92 years Forty two percent patients were primi gravid and 58% patients were multi gravida. Forty three percent patients were primi para while 57% patients were multi para. Ninety percent babies were alive while 10% babies were still birth. Conclusion: Our study concludes that the frequency of still births was 10% in obese pregnant women. Keywords: still births, obese, pregnant women, primi para, WHO.

Aim: To determine the efficacy of antenatal corticosteroid in the prevention of respiratory distress syndrome of the neonates in women undergoing elective cesarean section at term pregnancy. Study design: Descriptive case series Place and duration of study: Department of Obstetrics and Gynecology, Lady Reading Hospital, Peshawar from 6th December 2018 to 6th May 2019. Methodology: One hundred and seventy five women were enrolled. The women after taking complete history with obstetrical examination and antenatal corticosteroid administration i.e. 12 mg dexamethasone IM (two doses 12 hours apart) were observed. The caesarean section was performed by experienced obstetrician having minimum of five years of experience after 24 hours and within seven days of the second dose of dexamethasone. All the neonates were carefully examined in NICU for the detection of respiratory distress syndrome. All these observations were done under supervision of an expert pediatrician having minimum of five years of experience. Results: The mean age was 28±11.34 years. Thirty five percent patients had POG range 37+ weeks while 65% patients had POG range 38+ weeks. Mean POG was 37±1.12 weeks. More over antenatal corticosteroid was effective in 97% patients and was not effective in 3% patients. Conclusion: The antenatal corticosteroid was 97% effective in the prevention of respiratory distress syndrome of the neonates, in women undergoing ELSC at term after elective caesarean section for term pregnancy. Keywords: Efficacy, Antenatal corticosteroid, Respiratory distress syndrome, Neonates, Elective C- section,

Objective: To compare adverse feto-maternal outcome between women with early and late onset preeclampsia.Methodology: This cross sectional study was conducted in Gynecology and Obstetrics and Gynecology Department, Lady Reading Hospital, Peshawar from March 2016 to September 2016. A total of 254 patients having singleton pregnancy of more than 20 weeks were included. Week 34 was used as a cutoff to classify patients into Early Onset Preeclampsia (EOPE) and Late Onset Preeclampsia (LOPE). All the subjects were followed up till one week after delivery to compare adverse fetomaternal outcome. SPSS version 25 was used for data analysis.Results: Out of 254 patients, 172 (67.7%) patients had LOPE while 82 (32.3%) presented with EOPE. The mean Body Mass Index (BMI) for EOPE and LOPE was 25.25±1.70kg/m 2 and 25.97±2.03kg/m 2 , respectively. Most of the patients were multigravida in both groups, 43 (52.4%) in EOPE and 122 (70.93%) in LOPE. Preterm birth was more common in the EOPE (n=49, 59.75%) as compared to LOPE (n=60, 34.88%) with a p-value of ≤0.05. LOPE group had more cesarean sections (n=62, 36.02%) than EOPE (n=16, 19.53%) with a p-value of ≤0.05. Neonatal Intensive Care Unit (NICU) admissions were more common in EOPE group (60.92%) as compared to LOPE (41.82%) having a p-value of ≤0.05. Neonatal deaths and small for gestational age was found to be insignificant in the two groups. Conclusion:Preterm birth and NICU admissions were more common in EOPE while cesarean section was more commonly done in LOPE.