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ABSTRACT105 hort of patients with type 2 diabetes (T2D). The criteria of inclusion were patients with T2D of both genders using oral glucose-lowering medication(s) alone and/or with once-or twice-daily insulin. The criteria of exclusion were patients with a history of hematological, neoplastic, renal, hepatic or thyroid diseases, or patients receiving treatment with anti-inflammatory drugs. Patients with acute or chronic infections and autoimmune disease also excluded from the study. A total number of fifty-two patients (12 male and 40 females) with a median age of 57 year admitted in this study. Anthropometric measurements that related to the cardio-metabolic risk factors were measured. They included height (m), weight (kg), waist circumference (cm) and hip circumference (cm). The body mass index (BMI) and waist/hip ratio (W/H) were calculated. According to the BMI values the patients were categorized: normal (BMI < 25 kg/m2), over weight (BMI: 25-29 kg/m2), and obese (BMI: ≥ 30 kg/m2). A value of W/H ratio > 0.9 (male) and 0.8 (female) indicated central obesity.The blood pressure was measured on sitting position and the mean of three readings recorded. Pulse and mean arterial pressures calculated using the following formula: Pulse pressure (mm Hg) = Systolic blood pressure -diastolic blood pressure Mean arterial blood pressure = Diastolic blood pressure + 1/3 (Pulse pressure)Participants enrolled in the study subjected to echocardiography (B mode) investigation. The echocardiography investigation performed from the patient left side so that the transducer (with a frequency of 2-4MHz) is at the long axis of the heart. Echocardiography data that related to systolic and diastolic left ventricular dysfunction were recorded and these included: shortening fraction (%), stroke vol-