Li ing social restrictions is one of the most critical decisions that public health authorities have to face during a pandemic such as COVID-. This work focuses on the risk associated with such a decision. We have called the period from the re-opening decision to epidemic expiration the 'final epidemic phase', and considered the critical epidemic conditions which could possibly emerge in this phase. The factors we have considered include: the proportion of asymptomatic cases, a mitigation strategy based on testing and the average duration of infectious states. By assuming hypothetical configurations at the time of the re-opening decision and the partial knowledge concerning epidemic dynamics available to public health authorities, we have analyzed the risk of the re-opening decision based on possibly unreliable estimates. We have presented a discrete-time stochastic model with state-dependent transmission probabilities and multi-agent simulations. Our results show the di erent outcomes produced by di erent proportions of undetected asymptomatic cases, di erent probabilities of asymptomatic cases detected and contained, and a multivariate analysis of risk based on the average duration of asymptomatic and contained states. Finally, our analysis highlights that enduring uncertainty, typical of this pandemic, requires a risk analysis approach to complement epidemiological studies.

No abstract

Understanding the effects of individual awareness on epidemic phenomena is important to comprehend the coevolving system dynamic, to improve forecasting, and to better evaluate the outcome of possible interventions. In previous models of epidemics on social networks, individual awareness has often been approximated as a generic personal trait that depends on social reinforcement, and used to introduce variability in state transition probabilities. A novelty of this work is to assume that individual awareness is a function of several contributing factors pooled together, different by nature and dynamics, and to study it for different epidemic categories. This way, our model still has awareness as the core attribute that may change state transition probabilities. Another contribution is to study positive and negative variations of awareness, in a contagion-behavior model. Imitation is the key mechanism that we model for manipulating awareness, under different network settings and assumptions, in particular regarding the degree of intentionality that individuals may exhibit in spreading an epidemic. Three epidemic categories are considered—disease, addiction, and rumor—to discuss different imitation mechanisms and degree of intentionality. We assume a population with a heterogeneous distribution of awareness and different response mechanisms to information gathered from the network. With simulations, we show the interplay between population and awareness factors producing a distribution of state transition probabilities and analyze how different network and epidemic configurations modify transmission patterns.

Li ing social restrictions is one of the most critical decisions that public health authorities have to face during a pandemic such as COVID-. This work focuses on the risk associated with such a decision. We have called the period from the re-opening decision to epidemic expiration the 'final epidemic phase', and considered the critical epidemic conditions which could possibly emerge in this phase. The factors we have considered include: the proportion of asymptomatic cases, a mitigation strategy based on testing and the average duration of infectious states. By assuming hypothetical configurations at the time of the re-opening decision and the partial knowledge concerning epidemic dynamics available to public health authorities, we have analyzed the risk of the re-opening decision based on possibly unreliable estimates. We have presented a discrete-time stochastic model with state-dependent transmission probabilities and multi-agent simulations. Our results show the di erent outcomes produced by di erent proportions of undetected asymptomatic cases, di erent probabilities of asymptomatic cases detected and contained, and a multivariate analysis of risk based on the average duration of asymptomatic and contained states. Finally, our analysis highlights that enduring uncertainty, typical of this pandemic, requires a risk analysis approach to complement epidemiological studies.