This paper discusses the development method of strain sensors based on acicular single crystal compound TlInTe 2 is grown by Bridgman-Stockbarger technique. Creating mechanically reliable ohmic contacts on said obtained single crystals was carried out directly by spot welding wires corresponding to the ends of the capacitor discharge heated in a stream of inert gas from the single crystal TlİnTe 2. This method of creating contacts proved effective and reliable. Sensors made by this manner stuck to the calibrated beams of steel thickness of 1 mm, a length of 30 mm and a corresponding optimal regime got sensors with a maximum piezo-sensitivity. It was found that if enshrined at one end of a thin steel sheet with glued crystals TlİnTe 2 initiate periodic mechanical vibrations to the same frequency, occurs conductivity modulation. The effect of piezo-modulation conductance depending on the degree of deformation, illumination in interval of deformation and lux illumination in room temperature were studied. The study showed that the more mechanical deformation and illumination are, the more modulation amplitude is. We studied the modulation of the conductivity of crystals during mechanical deformation values of 8, 14, 19, 23 and 27 × 10 −5 and illuminance 1000, 2750, 4750 and 6500 suites. Investigations the level piezo-signal depending on the amplitude of mechanical vibrations at frequency of 85 Hz, it is found that with increasing magnitude of the mechanical deformation of 7 × 10 −5 and 26 × 10 −5 amplitude increases six times. It is shown that the piezoresistive effect is clearly manifested in dynamic mode. Additional conductivity occurs during mechanical deformation. When the illuminated samples piezoconductivity magnitude increases linearly.