Objective: The present investigation includes the preliminary screening of phytochemicals and evaluation of an in vitro antidiabetic activity of Psidium guajava leaves extracts. Materials and Methods: Plant material was subjected to the extract preparation by soxhlet apparatus by using various solvents such as aqueous, ethanol, chloroform, petroleum ether and hexane. The various kinds of phytochemicals were detected and then in vitro antidiabetic activity of P. guajava leaves were detected by using alpha amylase and alpha glucosidase enzyme in an in vitro model. Results: The study reveals the presence of phytochemicals such as carbohydrate, tannin, flavonoids, phenols etc., Among the various extracts the aqueous and ethanolic extracts which contains the large number of phytoconstituents. The P. guajava leaves has been successfully inhibited both the enzymes in an in vitro model. The aqueous extracts of P. guajava leaves inhibited the alpha amylase and alpha glucosidase enzymes as 72.1% and 74.8%respectively. The ethanolic extract of P. guajava leaves inhibited the alpha amylase and alpha glucosidase enzymes as 97.5% and 91.8% respectively. Conclusion: From the results obtained in the current studies, the P. guajava leaves have a prominent antidiabetic property in an in vitro model and further studies can be carried out in an in vivo model and the isolation of activie compound from P. guajava leaves extract is needed.
Psidium guajava Linn. possesses useful medicinal benefits. It has been recognized as the medicinally essential phytoconstituents, such as phenolic, flavonoid and carotenoid. Numerous pharmacological investigation have confirmed that the ability of this plant is to exhibit antimicrobial, antidiabetic, cardioprotective, neuroprotective, hepatoprotective, antioxidant and anticancer activities and it supports the traditional uses. This is a comprehensive of the phytoconstituents and pharmacological benefits.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.