In recent research from the total number of new cancer cases in Africa about 29.46% and in Ethiopia 31.85% are breast cancer cases. 25.84% of all cancer related death is from breast cancer. One of the challenges in the treatment of breast cancer is early detection. Researchers agreed that, improving the preventive mechanism of breast cancer is an early predicting and detecting model. Research efforts are continuing to present different solution approaches using advanced techniques of Artificial intelligence (AI), Machine learning (ML), Deep Learning (DL), and Computational Intelligence as well. A genetic algorithm is a hyper-parameter optimization algorithm that belongs to the class of evolutionary algorithms. Genetic Algorithm (GA) is used for complex search spaces for search and optimization. This reviewed literature paper shows the positive effect of GA in the diagnosis of breast cancer on AI algorithms.